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HCMBMAG-22K MILLIPLEX MAP Human Cancer/ Metastasis Biomarker Magnetic Bead Panel - Cancer Multiplex Assay

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Replacement Information

Key Spec Table

Analytes AvailableSpecies ReactivityKey ApplicationsDetection Methods
DKK-1 GDF-15 NSE OPG Osteonectin (SPARC) Periostin TRAP5 TWEAK YKL40 HMplexLuminex xMAP
Catalogue NumberHCMBMAG-22K
Trade Name
DescriptionMILLIPLEX MAP Human Cancer/ Metastasis Biomarker Magnetic Bead Panel - Cancer Multiplex Assay
OverviewThe MILLIPLEX MAP Human Cancer/Metastasis Biomarker Panel 1 contains nine metastasis biomarkers that have also been identified in a variety of tumor types. Coupled with the Luminex® xMAP® platform in magnetic bead format, this panel enables researchers to focus on discovery with the advantage of simultaneous quantitative multiplex detection leading to speed and sensitivity.
Background InformationMetastasis is a complex process in which tumor cells leave the primary tumor site and migrate to other parts of the body via blood and lymph vessels or by tumor invasion of surrounding tissues and organs. Breaking away from the primary tumor, cancer cells attach to and degrade extracellular matrix proteins that separate tumor from surrounding tissues to escape into the stroma. Where metastases form often depends on the primary tumor. Bone metastases, for example, tend to arise from breast, prostate and kidney tumors. This organ/tissue specificity seems to involve chemical signals from both chemokines and growth factors.
Product Information
Detection methodLuminex xMAP
ConfigurationDesign your multiplex kit by choosing available analytes within this panel.
Precision, %
  • Intra Assay: < 10%
  • Inter Assay: < 16%
Panel TypeMAGNETIC Circulating Cancer
Quality LevelMQ200
ApplicationCirculating Cancer and Metastasis Biomarker Bead-Based Multiplex Assays using the Luminex technology enables the simultaneous analysis of multiple oncology biomarkers in various tumor types in human serum, plasma and cell culture samples.
Key Applications
  • Multiplexing
Application Notes• This is an overnight incubation assay.
• This assay requires 25 μL of 1:10 diluted serum and plasma or tissue/cell culture supernatant
Biological Information
Species Reactivity
  • Human
Analytes Available
  • DKK-1
  • GDF-15
  • NSE
  • OPG
  • Osteonectin (SPARC)
  • Periostin
  • TRAP5
  • YKL40
Assay PanelEverything you need in a single kit.
Cross ReactivityCross-reactivity between the antibodies and any of the other analytes in this panel is non-detectable or negligible.
  • 70% - 105%
Physicochemical Information
  • Refer to kit protocol for sensitivities of individual biomarkers.
Standard Curve Range
  • DKK-1: 0.007 – 30 ng/mL
  • GDF15: 0.002 – 10 ng/mL
  • NSE: 0.036 – 150 ng/mL
  • OPG: 0.007 – 30 ng/mL
  • Osteonectin (SPARC): 0.976 – 4,00 0ng/mL
  • Periostin: 0.195 – 800 ng/mL
  • TRAP5: 0,019 – 80 ng/mL
  • TWEAK: Refer to the QC analysis sheet for exact concentration
  • YKL40: 0,048 - 20 ng/mL
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsRecommended storage for kit components is 2 - 8°C.
Packaging Information
Material Size96-well plate
Transport Information
Supplemental Information



Protocol- HCMBMAG-22K

MILLIPLEX MAP Human Cancer/ Metastasis Biomarker Magnetic Bead Panel - Cancer Multiplex Assay SDS


Safety Data Sheet (SDS) 


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Technical Info

96 well Template 2 Up
96 well Template Single
HCMBMAG-22K xPonent Protocol Template Version Magpix
HCMBMAG-22K xPonent Standard Template Version Magpix
Quality Control Range Sheet- HCMB-115 and HCMB-215
Quality Control Ranges: Human Cancer Metastasis Biomarker Magnetic Bead Panel

Data Sheet

Full Service Custom-built Assays

Newsletters / Publications

Article: Detection and localization of surgically resectable cancers with a multi-analyte blood test