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MCVD1MAG-77K MILLIPLEX MAP Mouse Cardiovascular Disease (CVD) Magnetic Bead Panel 1 - Cardiovascular Disease Multiplex Assay

MCVD1MAG-77K
Design And Price Your Kit

Overview

Replacement Information

Key Spec Table

Analytes AvailableSpecies ReactivityKey ApplicationsDetection Methods
proMMP-9 PAI-1 (Total) sE-Selectin sICAM-1 Thrombomodulin Pecam-1 sP-Selectin MMplexLuminex xMAP
Description
Catalogue NumberMCVD1MAG-77K
Trade Name
  • MILLIPLEX
DescriptionMILLIPLEX MAP Mouse Cardiovascular Disease (CVD) Magnetic Bead Panel 1 - Cardiovascular Disease Multiplex Assay
Background InformationCardiovascular disease, particularly atherosclerotic vascular disease, is a leading cause of global mortality, accounting for 30% of all global deaths (WHO, 2010). Now widely recognized, inflammatory mechanisms play a vital role in the initiation, maintenance and progression of vascular disease with a strong correlation between inflammatory markers and prognosis in acute and chronic coronary artery disease. In addition, numerous studies have demonstrated an association of obesity and diabetes with cardiovascular risk factors.
References
Product Information
Detection methodLuminex xMAP
ConfigurationDesign your multiplex kit by choosing available analytes within this panel.
Precision, %
  • Inter-assay: <15%
  • Intra-assay: <10%
Panel TypeMAGNETIC Cardiovascular
Quality LevelMQ200
Applications
ApplicationThis MILLIPLEX MAP Mouse Cardiovascular Disease Magnetic Bead Panel 1 includes the following analytes: sE-Selectin, sICAM-1, Pecam-1, sP-Selectin, PAI-1 (total), proMMP-9 & Thrombomodulin.
Key Applications
  • Multiplexing
Application Notes• This kit may be used for the analysis of Mouse serum, plasma or tissue culture supernatant samples
• Overnight incubation is recommended
• This assay utilizes as little as 5uL of sample (a 1:20 dilution for plasma or serum is recommended)
Biological Information
Species Reactivity
  • Mouse
Analytes Available
  • proMMP-9
  • PAI-1 (Total)
  • sE-Selectin
  • sICAM-1
  • Thrombomodulin
  • Pecam-1
  • sP-Selectin
Cross ReactivityNon-detectable within the panel
Accuracy
  • 88–99%
Physicochemical Information
Sensitivity
  • sE-Selectin: 0.033 ng/mL
  • sICAM-1: 0.013 ng/mL
  • proMMP-9: 0.008 ng/mL
  • PAI-1 (total): 0.012 ng/mL
  • Pecam-1 0.012 ng/mL
  • sP-Selectin: 0.429 ng/mL
  • Thrombomodulin: 0.039 ng/mL
Linearity of DilutionContact technical services for linearity of dilution.
Standard Curve Range
  • sE-Selectin: 0.049-200 ng/mL
  • proMMP-9: 0.012-50
  • sICAM-1: 0.007-30
  • PAI-1 (total): 0.018-75
  • Pecam-1: 0.024-100
  • sP-Selectin: 0.439-1800
  • Thrombomodulin: 0.024-100
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Packaging Information
Material Size96-well plate
Transport Information
Supplemental Information
Specifications

Documentation

Protocols

Title
Mouse CVD Magnetic Bead Panel 1

MILLIPLEX MAP Mouse Cardiovascular Disease (CVD) Magnetic Bead Panel 1 - Cardiovascular Disease Multiplex Assay SDS

Title

Safety Data Sheet (SDS) 

References

Reference overviewPub Med ID
Effects of dietary strawberry powder on blood lipids and inflammatory markers in obese human subjects.
Zunino, SJ; Parelman, MA; Freytag, TL; Stephensen, CB; Kelley, DS; Mackey, BE; Woodhouse, LR; Bonnel, EL
The British journal of nutrition  108  900-9  2012

Show Abstract
22068016 22068016

Brochure

Title
A closer look at immunoassay platforms. Beyond fit for purpse. Bring your biomarkers to life with Merck Millipore Immunoassay Platform Solutions.
Custom Immunoassay Menu of Services
The Power of Biomarker Analysis

Technical Info

Title
96 well Template 2 Up
96 well Template Single
Quality Control Ranges MILLIPLEX® MAP Mouse Cardiovascular Disease (CVD) Panel 1

Data Sheet

Title
Full Service Custom-built Assays (Merck)

Posters

Title
MILLIPLEX MAP: Exercise, Signaling, and Your Brain