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RBN1MAG-31K MILLIPLEX MAP Rat Bone Magnetic Bead Panel 1 - Bone Metabolism Multiplex Assay

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Replacement Information

Key Spec Table

Analytes AvailableSpecies ReactivityKey ApplicationsDetection Methods
ACTH DKK-1 FGF-23 Insulin Leptin Osteoprotegerin PTH SOST RMplexLuminex xMAP
Catalogue NumberRBN1MAG-31K
Trade Name
DescriptionMILLIPLEX MAP Rat Bone Magnetic Bead Panel 1 - Bone Metabolism Multiplex Assay
Background InformationEMD Millipore recognizes the need to better understand the role that bone metabolism biomarkers play in preserving normal bone structure and in the development of disease. Bone metabolism is the dynamic process of ongoing bone deposition and resorption, controlled by osteoblasts, osteocytes, and osteoclasts. While osteoblasts and osteocytes (osteoblasts surrounded by matrix) are responsible for bone deposition, osteoclasts are responsible for bone resorption. Both are required to maintain bone structure, as well as an adequate supply of calcium. To maintain this metabolic balance these cells rely on complex signaling pathways involving hormones and cytokines to achieve the appropriate rates of growth and differentiation.
Product Information
Detection methodLuminex xMAP
ConfigurationDesign your multiplex kit by choosing available analytes within this panel.
Precision, %
  • Intra-assay: <10
  • Inter-assay: <15
Panel TypeMAGNETIC Bone
Quality LevelMQ200
ApplicationThis MILLIPLEX MAP Rat Bone Magnetic Bead Panel 1 is a Bone Metabolism multiplex assay. The analytes available for this multiplex kit are: ACTH, Insulin, Leptin, Osteoprotegerin, DKK-1, SOST, FGF-23, PTH.
Key Applications
  • Multiplexing
Application Notes• No cross reactivity between the antibodies for an analyte in these panels were observed. All assays can be ran as a same day or overnight incubation assay.

• The Rat Bone Panel 1 (RBN1MAG-31K) is designed for measurement of serum or plasma samples and can be assayed as a same day or overnight incubation assay.
Biological Information
Species Reactivity
  • Rat
Analytes Available
  • ACTH
  • DKK-1
  • FGF-23
  • Insulin
  • Leptin
  • Osteoprotegerin
  • PTH
  • SOST
Cross ReactivityThe antibody pairs in each panel do not show cross reactivity to the other analytes within the panel
  • 88–105%
Physicochemical Information
  • 0.8 - 42.2 pg/mL
Linearity of DilutionPlease contact technical support for information.
Standard Curve Range
  • ACTH and OPG: 10-40,000 pg/mL
  • DKK-1: 12-50,000 pg/mL
  • Insulin: 31-125,000 pg/mL
  • Leptin: 7-30,000 pg/mL
  • SOST: 5-20,000 pg/mL
  • FGF-23: 22-90,000 pg/mL
  • PTH: 0.4-1,500 pg/mL
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Packaging Information
Material Size96-well plate
Transport Information
Supplemental Information
Global Trade Item Number
Catalogue Number GTIN
RBN1MAG-31K 04053252988035



Protocol- RBN1MAG-31K

MILLIPLEX MAP Rat Bone Magnetic Bead Panel 1 - Bone Metabolism Multiplex Assay SDS


Safety Data Sheet (SDS) 


Reference overviewPub Med ID
The preclinical efficacy, selectivity and pharmacologic profile of MK-5932, an insulin-sparing selective glucocorticoid receptor modulator.
Brandish, PE; Anderson, K; Baltus, GA; Bai, C; Bungard, CJ; Bunting, P; Byford, A; Chiu, CS; Cicmil, M; Corcoran, H; Euler, D; Fisher, JE; Gambone, C; Hasbun-Manning, M; Kuklin, N; Landis, E; Lifsted, TQ; McElwee-Witmer, S; McIntosh, IS; Meissner, RS; Miao, J; Mitchell, HJ; Musselman, A; Schmidt, A; Shin, J; Szczerba, P; Thompson, CD; Tribouley, C; Vogel, RL; Warrier, S; Hershey, JC
European journal of pharmacology  724  102-11  2014

Show Abstract
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Technical Info

96 well Template 2 Up
96 well Template Single
Quality Control Range Sheet- RBN31-110 and RBN31-210
Quality Control Ranges: Milliplex Rat Bone Panel and Milliplex Rat Osteopontin Single Plex Kit
RBN1MAG-31K xPonent Protocol Template Version Magpix

Data Sheet

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