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03-32-5032 MMP-2/MMP-7 Substrate, Fluorogenic - Calbiochem

Extremely sensitive fluorogenic substrate for matrix metalloproteinases (MMPs).

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
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03-32-5032
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Overview

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      		 Plastic ampoule 1 mg
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      Description
      OverviewExtremely sensitive fluorogenic substrate for matrix metalloproteinases (MMPs). Suitable for assessment of total activity in crude preparations by continuous assays (kcat/Km = 1.7 x 105 M-1sec-1 for MMP-7 and 6.3 x 105 M-1sec-1 for MMP-2).
      Catalogue Number03-32-5032
      Brand Family Calbiochem®
      References
      ReferencesKnight, C.G., et al. 1992. FEBS Lett. 296, 263.
      Product Information
      ATP CompetitiveN
      FormYellow solid
      FormulationSupplied as a trifluoroacetate salt.
      Hill FormulaC₄₉H₆₈N₁₄O₁₅
      Chemical formulaC₄₉H₆₈N₁₄O₁₅
      HS Code2922 50 99
      ReversibleN
      Quality LevelMQ200
      Applications
      Biological Information
      Primary TargetFluorogenic substrate for matrix metalloproteinases (MMPs)
      Primary Target IC<sub>50</sub>kcat/Km = 1.7 x 105 M-1sec-1 for MMP-7 and 6.3 x 105 M⁻¹ sec⁻¹ for MMP-2
      Purity≥95% by HPLC
      Physicochemical Information
      Cell permeableN
      Emission max.
      Excitation max.
      Peptide SequenceMCA-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH₂ ·TFA [Dpa = N-3-(2,4-dinitrophenyl)-L-2,3-diaminopropionyl]
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Protect from Moisture Protect from moisture
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      03-32-5032-1MG 04055977206777

      Documentation

      MMP-2/MMP-7 Substrate, Fluorogenic - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      MMP-2/MMP-7 Substrate, Fluorogenic - Calbiochem Certificates of Analysis

      TitleLot Number
      03-32-5032

      References

      Reference overview
      Knight, C.G., et al. 1992. FEBS Lett. 296, 263.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision21-June-2013 JSW
      DescriptionExtremely sensitive fluorogenic substrate for matrix metalloproteinases (MMPs; excitation maximum: 325 nm; emission maximum: 393 nm). Suitable for assessment of total activity in crude preparations by continuous assays (kcat/Km = 1.7 x 105 M-1sec-1 for MMP-7 and 6.3 x 105 M-1sec-1 for MMP-2).
      FormYellow solid
      FormulationSupplied as a trifluoroacetate salt.
      Chemical formulaC₄₉H₆₈N₁₄O₁₅
      Peptide SequenceMCA-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH₂ ·TFA [Dpa = N-3-(2,4-dinitrophenyl)-L-2,3-diaminopropionyl]
      Purity≥95% by HPLC
      Solubility20% Acetic Acid (1 mg/ml)
      Storage Protect from moisture
      -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Standard Handling
      ReferencesKnight, C.G., et al. 1992. FEBS Lett. 296, 263.

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      Categories

      Life Science Research > Proteins and Enzymes > Substrate & Control Proteins > Protease Substrates