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855116 Methyl Indole AM resin

Overview

Replacement Information

Key Spec Table

CAS #
9003-70-7
Description
Catalogue Number855116
Replaces01-64-0451
Brand Family Novabiochem®
Background Information[3-((Methyl-Fmoc-amino)-methyl)indol-1-yl]acetyl AM resin is an extremely useful support for the production of N-methyl substituted carboxamides and sulfonamides, as well as peptide N-methylamides [1]. After first removing the Fmoc group, loading of the resin with Fmoc-amino acids can be effected using HATU/DIPEA. Cleavage with TFA directly provides the product N-methylamide.

The product number for this product was previously 01-64-0451.

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References
Product Information
CAS number9003-70-7
HS Code3903 90 90
Structure formula ImageStructure formula Image
Quality LevelMQ300
Applications
Biological Information
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Storage class10 - 13 Other liquids and solids
WGKWGK 1 slightly hazardous to water
Safety Information
Product Usage Statements
Storage and Shipping Information
StorageStore at +2°C to +8°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Colour (visual)white to yellow to beige
Appearance of substance (visual)beads
Loading (Photometric determination of the Fmoc-chromophore liberated upon treatment with DBU/DMF)0.60 - 1.00 mmol/g
Swelling Volume (in CH₂Cl₂)lot specific result
The polymer matrix is copoly (styrene-1 % DVB), 100 - 200 mesh.

Documentation

Methyl Indole AM resin SDS

Title

Safety Data Sheet (SDS) 

Citations

Title
[1] K. G. Estep, et al. (1998) J. Org. Chem., 63, 5300.