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480875 Neurotrophin-3, Human, Recombinant, E. coli

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: rhNT-3

480875
  
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      Overview

      Replacement Information

      Key Spec Table

      Purity
      ≥98% by SDS-PAGE
      Description
      Overview

      This product has been discontinued.





      Recombinant, human neurotrophin-3 expressed in E. coli. A potent neurotrophic factor that supports the survival of certain CNS neurons. Increases DNA-binding of several transcription factors.
      Catalogue Number480875
      Brand Family Calbiochem®
      SynonymsrhNT-3
      References
      ReferencesCarter, B.D., et al. 1996. Science 272, 542.
      Iwata, E., et al. 1996. Biochim. Biophys. Acta 1311, 85.
      Zhou, X.F., and Rush, R.A. 1994. Brain Res. 643, 162.
      Hohn, A., et al. 1990. Nature 344, 339.
      Mainsonpierre, P.C., et al. 1990. Science 247, 1447.
      Product Information
      FormLyophilized solid
      Quality LevelMQ100
      Applications
      Biological Information
      Biological activityFully biologically active when compared to native NT-3. EC₅₀ = 50 ng/ml for induction of choline acetyltransferase activity in rat basal forebrain primary septal culture cells
      Purity≥98% by SDS-PAGE
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Protect from Moisture Protect from moisture
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Avoid freeze/thaw cycles of solutions. Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      480875 0

      Documentation

      Neurotrophin-3, Human, Recombinant, E. coli SDS

      Title

      Safety Data Sheet (SDS) 

      References

      Reference overview
      Carter, B.D., et al. 1996. Science 272, 542.
      Iwata, E., et al. 1996. Biochim. Biophys. Acta 1311, 85.
      Zhou, X.F., and Rush, R.A. 1994. Brain Res. 643, 162.
      Hohn, A., et al. 1990. Nature 344, 339.
      Mainsonpierre, P.C., et al. 1990. Science 247, 1447.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision11-August-2008 RFH
      SynonymsrhNT-3
      DescriptionRecombinant, human neurotrophin-3 expressed in E. coli. A potent neurotrophic factor that supports the survival of certain CNS neurons. Increases DNA-binding of several transcription factors.
      FormLyophilized solid
      Purity≥98% by SDS-PAGE
      Biological activityFully biologically active when compared to native NT-3. EC₅₀ = 50 ng/ml for induction of choline acetyltransferase activity in rat basal forebrain primary septal culture cells
      SolubilityReconstitute in 100 µl of sterile distilled H₂O or aqueous buffers. For more diluted solutions, add a stabilizing protein such as BSA (100 µg/ml).
      Storage Protect from moisture
      -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Avoid freeze/thaw cycles of solutions. Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Standard Handling
      Merck USA index14, 6487
      ReferencesCarter, B.D., et al. 1996. Science 272, 542.
      Iwata, E., et al. 1996. Biochim. Biophys. Acta 1311, 85.
      Zhou, X.F., and Rush, R.A. 1994. Brain Res. 643, 162.
      Hohn, A., et al. 1990. Nature 344, 339.
      Mainsonpierre, P.C., et al. 1990. Science 247, 1447.