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475914 Nystatin, Streptomyces noursei - CAS 1400-61-9 - Calbiochem

Nystatin, Streptomyces noursei, CAS 1400-61-9, is an antifungal antibiotic effective against yeast and mycoplasma. Acts as a cation-selective ionophore that exhibits selectivity for Na+.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Mycostatin

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      Overview

      Replacement Information

      Key Spec Table

      CAS #Empirical Formula
      1400-61-9C₄₇H₇₅NO₁₇
      Description
      OverviewA polyene antifungal antibiotic effective against yeast and mycoplasma. Induces loss of low molecular weight substances from cells with low selectivity. A cation-selective ionophore that exhibits selectivity for Na+. Increases the activity of Na+ - K+ pump.
      Catalogue Number475914
      Brand Family Calbiochem®
      SynonymsMycostatin
      References
      ReferencesGruwel, M.L., et al. 1995. Am J. Physiol. 268, H351.
      Opekarova, M., and Tanner, W. 1994. FEBS Lett. 360, 46.
      Stoos, B.A., et al. 1994. J. Am. Soc. Nephrol. 4, 1855.
      Skolink, P.R., et al. 1989. J. Infect. Dis. 160, 1056.
      Product Information
      CAS number1400-61-9
      FormOff-white to yellow solid
      Hill FormulaC₄₇H₇₅NO₁₇
      Chemical formulaC₄₇H₇₅NO₁₇
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      ApplicationNystatin, Streptomyces noursei, CAS 1400-61-9, is an antifungal antibiotic effective against yeast and mycoplasma. Acts as a cation-selective ionophore that exhibits selectivity for Na+.
      Biological Information
      Biological activityPotency: ≥3000 units/mg (anhydrous).
      Purity≥95% by HPLC (sum of two peaks)
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      RTECSRF5950000
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage +2°C to +8°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      475914 0

      Documentation

      Nystatin, Streptomyces noursei - CAS 1400-61-9 - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      Nystatin, Streptomyces noursei - CAS 1400-61-9 - Calbiochem Certificates of Analysis

      TitleLot Number
      475914

      References

      Reference overview
      Gruwel, M.L., et al. 1995. Am J. Physiol. 268, H351.
      Opekarova, M., and Tanner, W. 1994. FEBS Lett. 360, 46.
      Stoos, B.A., et al. 1994. J. Am. Soc. Nephrol. 4, 1855.
      Skolink, P.R., et al. 1989. J. Infect. Dis. 160, 1056.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision10-December-2016 JSW
      SynonymsMycostatin
      DescriptionA polyene antifungal antibiotic effective against yeast and mycoplasma. Induces loss of low molecular weight substances from cells with low selectivity. A cation selective ionophore that exhibits selectivity for Na+. Increases the activity of the Na+-K+ pump. Suggested concentration is 50 µg/ml.
      FormOff-white to yellow solid
      CAS number1400-61-9
      RTECSRF5950000
      Chemical formulaC₄₇H₇₅NO₁₇
      Structure formulaStructure formula
      Purity≥95% by HPLC (sum of two peaks)
      Biological activityPotency: ≥3000 units/mg (anhydrous).
      SolubilityDMSO (50 mg/ml)
      Storage Protect from light
      +2°C to +8°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
      Toxicity Standard Handling
      Merck USA index14, 6736
      ReferencesGruwel, M.L., et al. 1995. Am J. Physiol. 268, H351.
      Opekarova, M., and Tanner, W. 1994. FEBS Lett. 360, 46.
      Stoos, B.A., et al. 1994. J. Am. Soc. Nephrol. 4, 1855.
      Skolink, P.R., et al. 1989. J. Infect. Dis. 160, 1056.

      Related Products & Applications

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      Catalogue Number Description  
      475921 Nystatin, Streptomyces noursei, Sterile, Tissue Culture Grade - CAS 1400-61-9 - Calbiochem Show Pricing & Availability

      Categories

      Life Science Research > Inhibitors and Biochemicals > Biochemicals > Antibiotics > Antifungal Agents
      Life Science Research > Inhibitors and Biochemicals > Biochemicals > Ionophores