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526522 PIM1 Kinase Inhibitor IV

PIM1 Kinase Inhibitor IV MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: 4-(3-(4-Chlorophenyl)-2,1-benzisoxazol-5-yl)-2-pyrimidinamine

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      Overview

      Replacement Information

      Key Spec Table

      CAS #Empirical Formula
      477845-12-8C₁₇H₁₁ClN₄O
      Description
      Overview

      This product has been discontinued.



      A pyrimidinyl-benzisoxazolo compound that interacts with Lys67 and Glu121 at the PIM1 active site and inhibits PIM1 kinase activity with a Ki value of 0.091 µM.
      Catalogue Number526522
      Brand Family Calbiochem®
      Synonyms4-(3-(4-Chlorophenyl)-2,1-benzisoxazol-5-yl)-2-pyrimidinamine
      References
      ReferencesPierce, A.C., et al. 2008. J. Med. Chem. 51, 1972.
      Product Information
      CAS number477845-12-8
      FormYellow solid
      Hill FormulaC₁₇H₁₁ClN₄O
      Chemical formulaC₁₇H₁₁ClN₄O
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Purity≥97% by HPLC
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      S PhraseS: 22-24/25

      Do not breathe dust.
      Avoid contact with skin and eyes.
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage +2°C to +8°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      526522 0

      Documentation

      PIM1 Kinase Inhibitor IV SDS

      Title

      Safety Data Sheet (SDS) 

      PIM1 Kinase Inhibitor IV Certificates of Analysis

      TitleLot Number
      526522

      References

      Reference overview
      Pierce, A.C., et al. 2008. J. Med. Chem. 51, 1972.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision18-April-2011 RFH
      Synonyms4-(3-(4-Chlorophenyl)-2,1-benzisoxazol-5-yl)-2-pyrimidinamine
      DescriptionA pyrimidinyl-benzisoxazolo compound that interacts with Lys67 and Glu121 at the PIM1 active site and inhibits PIM1 kinase activity with a Ki value of 0.091 µM.
      FormYellow solid
      Intert gas (Yes/No) Packaged under inert gas
      CAS number477845-12-8
      Chemical formulaC₁₇H₁₁ClN₄O
      Structure formulaStructure formula
      Purity≥97% by HPLC
      SolubilityDMSO (5 mg/ml)
      Storage Protect from light
      +2°C to +8°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Standard Handling
      ReferencesPierce, A.C., et al. 2008. J. Med. Chem. 51, 1972.