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851090 TFFH

TFFH Tetramethylfluoroformamidinium hexafluorophosphate Novabiochem®. CAS 164298-23-1, molar mass 264.13 g/mol.

TFFH MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
CAS #: 164298-23-1 Molar Mass: 264.13 g/mol Hill Formula: C₅H₁₂F₇N₂P
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Overview

Replacement Information

Key Spec Table

CAS #Hill FormulaMolar Mass
164298-23-1C₅H₁₂F₇N₂P264.13 g/mol
Description
Catalogue Number851090
Brand Family Novabiochem®
Alternate Names
  • Tetramethylfluoroformamidinium hexafluorophosphate,Fluoro-N,N,N',N'-bis(tetramethylene)formamidinium hexafluorophosphate
Background InformationTFFH is an in situ coupling reagents which smoothly converts protected amino acids to the corresponding acid fluoride in the presence of base [1]. Acid fluorides have proven are highly effective at coupling hindered amino acids such as α, α-disubstituted amino acids [2].
References
Product Information
CAS number164298-23-1
Hill FormulaC₅H₁₂F₇N₂P
Molar Mass264.13 g/mol
Structure formula ImageStructure formula Image
Quality LevelMQ200
Applications
ApplicationTFFH Tetramethylfluoroformamidinium hexafluorophosphate Novabiochem®. CAS 164298-23-1, molar mass 264.13 g/mol.
Biological Information
Physicochemical Information
Melting Point104 - 108 °C
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Hazard Pictogram(s) Hazard Pictogram(s)
Hazard Pictogram(s)
Hazard Statement(s)H315: Causes skin irritation.
H318: Causes serious eye damage.
H335: May cause respiratory irritation.
Precautionary Statement(s)P261: Avoid breathing dust.
P264: Wash skin thoroughly after handling.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear protective gloves/ eye protection/ face protection.
P302 + P352: IF ON SKIN: Wash with plenty of water.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Signal WordDanger
Storage class10 - 13 Other liquids and solids
WGKWGK 3 highly hazardous to water
Safety Information
Product Usage Statements
Storage and Shipping Information
StorageStore at +2°C to +8°C.
Packaging Information
Transport Information
Supplemental Information
Specifications

Documentation

TFFH SDS

Title

Safety Data Sheet (SDS) 

Citations

Title
  • [1] L. A. Carpino, et al. (1995) J. Am. Chem. Soc., 117, 5401.
  • [1] S. A. Triolo, et al. in 'Peptides 1996, Proc. of 24th European Peptide Symposium', R. Ramage & R. Epton (Eds), Mayflower Scientific Ltd., Birmingham, 1998, pp. 839.