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662089 UCH-L3 Inhibitor - CAS 30675-13-9 - Calbiochem

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Ubiquitin C-Terminal Hydrolase L3 Inhibitor, Ubiquitin C-Terminal Esterase L3 Inhibitor, Ubiquitin Thiolesterase L3 Inhibitor, 4,5,6,7-Tetrachloroindan-1,3-dione

Primary Target: UCH-L3
662089
  
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      Overview

      Replacement Information

      Key Spec Table

      CAS #Empirical Formula
      30675-13-9C₉H₂Cl₄O₂
      Description
      Overview

      This product has been discontinued.



      We are offering TCID (Cat. No. SML1402) as a possible alternative. Please read the alternative product documentation carefully and contact technical service if you need additional information.






      A 1,3-indanedione compound that acts as a selective and potent inhibitor of UCH-L3 (IC50 = 0.6 µM) with ~125-fold greater selectivity over UCH-L1 (IC50 = 75 µM).
      Catalogue Number662089
      Brand Family Calbiochem®
      SynonymsUbiquitin C-Terminal Hydrolase L3 Inhibitor, Ubiquitin C-Terminal Esterase L3 Inhibitor, Ubiquitin Thiolesterase L3 Inhibitor, 4,5,6,7-Tetrachloroindan-1,3-dione
      References
      ReferencesLiu, Y., et al. 2003. Chem. Biol. 10, 837.
      Product Information
      CAS number30675-13-9
      ATP CompetitiveN
      FormOrange solid
      Hill FormulaC₉H₂Cl₄O₂
      Chemical formulaC₉H₂Cl₄O₂
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetUCH-L3
      Primary Target IC<sub>50</sub>0.6 µM
      Purity≥92% by HPLC
      Physicochemical Information
      Cell permeableN
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
      Toxicity Standard Handling
      Storage +2°C to +8°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      662089 0

      Documentation

      UCH-L3 Inhibitor - CAS 30675-13-9 - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      UCH-L3 Inhibitor - CAS 30675-13-9 - Calbiochem Certificates of Analysis

      TitleLot Number
      662089

      References

      Reference overview
      Liu, Y., et al. 2003. Chem. Biol. 10, 837.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision08-January-2008 JSW
      SynonymsUbiquitin C-Terminal Hydrolase L3 Inhibitor, Ubiquitin C-Terminal Esterase L3 Inhibitor, Ubiquitin Thiolesterase L3 Inhibitor, 4,5,6,7-Tetrachloroindan-1,3-dione
      DescriptionA selective and potent inhibitor of ubiquitin C-terminal hydrolase L3 (UCH-L3) (IC50 = 600 nM) that exhibits ~125-fold greater selectivity for UCH-L3 compared to UCH-L1 (IC50 = 75 µM).
      FormOrange solid
      CAS number30675-13-9
      Chemical formulaC₉H₂Cl₄O₂
      Structure formulaStructure formula
      Purity≥92% by HPLC
      SolubilityDMSO (25 mg/ml)
      Storage Protect from light
      +2°C to +8°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Standard Handling
      ReferencesLiu, Y., et al. 2003. Chem. Biol. 10, 837.