切向流过滤装置
采用PELLICON®胶囊和卡匣的单程TFF系统
采用Pellicon®胶囊与卡匣的单程薄膜过滤技术，通过浓缩工艺流体实现流程优化，无需传统薄膜过滤的循环操作。该方案可简化工艺流程，在提升产能、浓缩度及产品回收率的同时缩小占地面积。此多功能应用还支持连续强化处理，将在线体积缩减与其他工艺步骤协同进行。
Pellicon® 胶囊
Pellicon® 胶囊与Ultracel® 膜胶囊融合，简化了超滤和透析过程，兼具操作便捷性与工艺灵活性。这款创新型一次性TFF胶囊采用独特的即插即用式无支架设计，经伽马射线灭菌处理，数分钟即可投入运行，可实现卓越的质量传递、通量及最佳回收率。
Pellicon® 2 滤盒
Pellicon® 2 滤盒适用于生物制品的超滤与透析过滤，包括多糖、病毒悬浮液及蛋白质溶液的浓缩、脱盐与缓冲液置换。Ultracel® 和 Biomax® 膜可实现高效超滤，而 Durapore® 膜则最适合微滤应用。
Pellicon® XL 50 滤盒
Pellicon® XL 50 盒式装置将超滤与微滤膜结合，具备线性可扩展性，适用于工艺开发或小批量处理。
Prostak™ 微滤模块
Prostak™ 微滤模块结构坚固、性能可靠，并具备就地蒸汽灭菌能力，适用于澄清、细胞收获及多用途灌注。其低滞留体积与开放通道设计可实现高产品回收率，并为处理剪切敏感材料提供温和流道。
支持资质认证、风险评估与工艺优化
作为产品组合的补充，Emprove®计划提供三类技术文件，支持开发与生产运营的不同阶段，包括资质认证、风险评估及工艺优化。这些文件以便捷格式整合全面的产品专属测试数据、质量声明及法规信息，助力简化合规需求。
Products
相关文章
- Tangential Flow Filtration in Downstream Bioprocessing
There are many options for tangential flow filtration (TFF) in downstream bioprocessing from multi-use to single-use TFF or batch TFF and single-pass TFF.
- Tangential Flow Filtration in the Antibody Drug Conjugate (ADC) Manufacturing Process
Find best practices for using Pellicon® Capsules in ADC processing as well as data from two studies using Pellicon® Capsules and Pellicon® cassettes in the ADC manufacturing process.
- Single-Pass Tangential Flow Filtration Implementation and Scaling
Get practical guidance on using single-pass tangential flow filtration in your downstream process and scaling between capsules and cassettes.
相关资源
- Application Note: Best Practices for Permeate-Controlled Tangential Flow Filtration
Process development and optimization for robust permeate-controlled TFF using microfiltration and open-ultrafiltration membranes.
- Performance Guide: Pellicon® Capsules with 100 and 300 kDa Ultracel® Membrane
Single-use tangential flow filtration devices offering high flux performance, reliable scalability, and enhanced operator safety for viral gene therapy applications.
- Data Sheet: Pellicon® Capsules with Ultracel® Membrane
Accelerate your therapy using our innovative single-use tangential flow filters with superior flux performance
- Data Sheet: Pellicon® 3 Cassettes with Ultracel® Membrane
The optimum tangential flow filtration devices for monoclonal antibodies and other therapeutic proteins.
- Data Sheet: Pellicon® 3 Cassettes with Biomax® Membrane
The device of choice for applications requiring higher yield, fast processing, and exceptional chemical resistance
- Data Sheet: Pellicon® 2 Filters and Holders
High performance tangential flow filters for biopharmaceutical process development, scale-up and scale-down, concentration, purification, and cell harvesting applications.
- Data Sheet: Prostak™ Microfiltration Modules
Prostak™ modules are tangential flow stacked plate membrane devices with open feed channels, made for use in Prostak™ tangential flow filtration (TFF) systems.
- Data Sheet: Pellicon® XL 50 Cassettes
Easy-to-use, high performance, linearly scalable tangential flow filtration cassette for process development work at volumes from 50 to 1000 mL
- Data Sheet: Pellicon® Single-Pass Tangential Flow Filtration
Pellicon® single-pass tangential flow filtration (single-pass TFF) is a versatile technology for more productive, high capacity and cost effective downstream processes that allows facilities to meet the demands of higher titer and connected or continuous processes
- Data Sheet: Ultracel® Membranes
The membrane of choice for ultra-low protein binding and robust performance during concentration and diafiltration of therapeutics
- Data Sheet: Biomax® Membranes
The membrane of choice for fast processing and exceptional chemical resistance
- Performance Guide: Pellicon® Capsules with Ultracel® Membrane
Innovative, high performance single-use tangential flow filtration devices that offer ease-of-use, operational flexibility, and enhanced operator safety.
- Application Note: Pellicon® Capsules for Single-use Tangential Flow Filtration
The Pellicon® Capsule is the first of its kind—a true single-use TFF device that streamlines bioprocessing with its innovative, simplified design and user-friendly features.
- Performance Guide: Pellicon® 3 Cassettes with Ultracel® Membrane
The tangential flow filtration devices of choice for demanding filtration processes requiring unbeatable performance consistency.
- Performance Guide: Pellicon® 3 Cassettes with Biomax® Membrane
The tangential flow filtration device of choice for demanding filtration processes requiring unbeatable performance consistency
- Application Note: Pellicon® 3 Cassettes with High Viscosity Feed Screen
Pellicon® 3 Cassettes with Ultracel® and Biomax® 30kD Membrane utilizing D screen geometry are engineered to efficiently process higher viscosity products.
- Application Note: Process Optimization and Scalability Evaluation of Pellicon® Capsules for Single-pass Tangential Flow Filtration of mAb-Based Biomolecules
Single-pass tangential flow filtration (SPTFF) is a method of ultrafiltration for the purposes of either volume reduction or protein concentration.
- White Paper: Streamlining Bioprocessing Using Pellicon® Cassettes for Single-pass Operation
Single-pass TFF is an enhanced approach to the existing TFF technology that has been used for the purification of monoclonal antibodies, therapeutic proteins, and vaccines at different steps within downstream processing
- Application Note: Closed Tangential Flow Filtration Processing at Benchtop Scale with Mobius® Assemblies
Mobius® assemblies offer a customizable, closed processing option for tangential flow filtration (TFF) operations.
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