alzheimer's disease
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Amyloid Precursor Protein Antibodies (Amyloid Precursor Protein Antibodies)
APP is the precursor molecule whose proteolysis generates beta amyloid (Aβ), a 37 to 49 amino acid peptide that is the primary component of amyloid plaques found in Alzheimer's disease patients.
171596 Sigma-Aldrichβ-Amyloid Peptide (1-42), Rat (β-Amyloid Peptide (1-42), Rat)
Predominant peptide found in the brain of patients with Alzheimer's Disease and Down's Syndrome. Promotes down-regulation of Bcl-2 and upregulation of Bax expression in neurons.
DR1001 Sigma-AldrichAnti-8-Hydroxyguanosine Goat pAb (Anti-8-Hydroxyguanosine Goat pAb)
This Anti-8-Hydroxyguanosine Goat polyclonal antibody detects 8-Hydroxydeoxyguanosine in Alzheimer's disease brain tissue. It is validated for use in ELISA and with paraffin sections.
SCR526 Sigma-AldrichAlzheimer’s In A Dish™ APPSL-GFP Lentivirus (Alzheimer’s In A Dish™ APPSL-GFP Lentivirus)
The APPSL-GFP lentivirus can be used to generate 3D cell culture models of Alzheimer’s Disease. The high-titer polycistronic lentiviral particles contain the APPSL and TagGFP2 proteins and can be used to infect human neural stem cells at high efficiency.
SCR527 Sigma-AldrichAlzheimer’s In A Dish™ PSEN1-RFP Lentivirus (Alzheimer’s In A Dish™ PSEN1-RFP Lentivirus)
The PSEN1-RFP lentivirus can be used to generate 3D cell culture models of Alzheimer’s Disease. The high-titer polycistronic lentiviral particles contain the PSEN1 and TagRFP2 proteins and can be used to infect human neural stem cells at high efficiency.
SCT073 Sigma-AldrichBioTracker NIR Amyloid-ß Plaque Imaging Dye (BioTracker NIR Amyloid-ß Plaque Imaging Dye)
Near-Infrared probe for live cell imaging of amyloid-ß (Aß) plaques, critical for the early detection of Alzheimer's disease.
SCT067 Sigma-AldrichBioTracker IRI-1 b-Amyloid Plaque Live Cell Dye (BioTracker IRI-1 b-Amyloid Plaque Live Cell Dye)
Live cell imaging probe for beta-amyloid plaques to study neurodegenrative diseases such as Alzheimer's disease.
SCC134 Sigma-AldrichIMG Mouse Microglial Cell Line (IMG Mouse Microglial Cell Line)
IMG microglial cells recapitulate key features of microglial cell activation and may be used to study neuroinflammatory responses underlying Alzheimer's disease.
MABN254 Sigma-AldrichAnti-amyloid beta peptide (MOAB-2), pan Antibody, clone 6C3 (Anti-amyloid beta peptide (MOAB-2), pan Antibody, clone 6C3)
Anti-amyloid beta peptide (MOAB-2), pan Antibody, clone 6C3 is an antibody against amyloid beta peptide (MOAB-2), pan, clone 6C3 for use in western blotting, IHC (Paraffin), Immunofluorescence, IP, Dot Blot.
MABN10 Sigma-AldrichAnti-Amyloid β Antibody, clone W0-2 (Anti-Amyloid β Antibody, clone W0-2)
Detect Amyloid β using this Anti-Amyloid β Antibody, clone W0-2 validated for use in WB, IH, ELISA.