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Merck

GRIK2

glutamate receptor, ionotropic, kainate 2

Sinónimos:
EAA4, GLR6, GLUK6, GLUR6, GluK2, MRT6
Especie:
ID UniProtKB:
ID del gen:
  • Human(2898) Summary: Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. The subunit encoded by this gene is subject to RNA editing at multiple sites within the first and second transmembrane domains, which is thought to alter the structure and function of the receptor complex. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene. Mutations in this gene have been associated with autosomal recessive mental retardation. [provided by RefSeq, Jul 2008]
  • Mouse(14806) glutamate receptor, ionotropic, kainate 2 (beta 2)
  • Rat(54257) glutamate receptor, ionotropic, kainate 2
  • chicken(428628) glutamate receptor, ionotropic, kainate 2
  • dog(481938) glutamate receptor, ionotropic, kainate 2
  • Thale Cress(836176) geminivirus rep interacting kinase 2
  • Zebrafish(556013) glutamate receptor, ionotropic, kainate 2
  • cow(615226) glutamate receptor, ionotropic, kainate 2
  • naked mole-rat(101697577) glutamate receptor, ionotropic, kainate 2
  • domestic guinea pig(100733104) glutamate receptor, ionotropic, kainate 2
  • sheep(101122701) glutamate receptor, ionotropic, kainate 2

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Small Molecule - Agonist

Product Number
Descripción
Especie
L-Glutamic acid hydrochloride, ≥99% (HPLC),
Especie
human
(±)-AMPA, solid,
Especie
rat
(S)-AMPA, ≥97%,
Especie
mouse, human, rat
Ácido kaínico monohydrate, ≥99% (TLC),
Especie
human, mouse, rat
(Aminomethyl)phosphonic acid, 99%,
Especie
rat, human

Small Molecule - Antagonist

Product Number
Descripción
Especie
CNQX, ≥98% (HPLC), solid,
Especie
rat
NBQX disodium salt hydrate, ≥98% (HPLC),
Especie
human
DNQX, ≥98% (TLC),
Especie
mouse, rat, human
(±)-AMPA, solid,
Especie
rat
(S)-AMPA, ≥97%,
Especie
mouse, human, rat

Antibodies

Product Number
Descripción
Reactividad de especies
Aplicación
Anti-GluR6/7 Antibody, clone NL9, rabbit monoclonal, culture supernatant, clone NL904, Upstate®,
Reactividad de especies
human, mouse, rat
Aplicación
immunoprecipitation (IP)
western blot
Anti-GRIK2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human, mouse, rat
Aplicación
immunohistochemistry
western blot
Anti-GRIK2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
Anti-GRIK2 (AB1) antibody produced in rabbit, IgG fraction of antiserum,
Reactividad de especies
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Aplicación
western blot
Anti-GRIK2 antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Aplicación
western blot

Small Molecule - Mixed Agonist/Antagonist

Product Number
Descripción
Especie
(±)-AMPA, solid,
Especie
rat
Ácido kaínico monohydrate, ≥99% (TLC),
Especie
human, mouse, rat
L-Glutamic acid, ReagentPlus®, ≥99% (HPLC),
Especie
rat, human
L-Glutamic acid, from non-animal source, meets EP testing specifications, suitable for cell culture, 98.5-100.5%,
Especie
rat, human
L-Glutamic acid, BioUltra, ≥99.5% (NT),
Especie
rat, human

esiRNA

Product Number
Descripción
Especie
MISSION® esiRNA, targeting human GRIK2 (1),
Especie
human
MISSION® esiRNA, targeting human GRIK2 (2),
Especie
human