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Merck

NDUFS7

NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase)

Sinónimos:
CI-20, CI-20KD, MY017, PSST
Especie:
ID UniProtKB:
ID del gen:
  • Human(374291) Summary: This gene encodes a protein that is a subunit of one of the complexes that forms the mitochondrial respiratory chain. This protein is one of over 40 subunits found in complex I, the nicotinamide adenine dinucleotide (NADH):ubiquinone oxidoreductase. This complex functions in the transfer of electrons from NADH to the respiratory chain, and ubiquinone is believed to be the immediate electron acceptor for the enzyme. Mutations in this gene cause Leigh syndrome due to mitochondrial complex I deficiency, a severe neurological disorder that results in bilaterally symmetrical necrotic lesions in subcortical brain regions. [provided by RefSeq, Jul 2008]
  • Mouse(75406) NADH dehydrogenase (ubiquinone) Fe-S protein 7
  • Rat(362837) NADH dehydrogenase (ubiquinone) Fe-S protein 7
  • domestic cat(101096448) NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase)
  • Zebrafish(796997) NADH dehydrogenase (ubiquinone) Fe-S protein 7, (NADH-coenzyme Q reductase)
  • chicken(770724) NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase)
  • domestic guinea pig(100731963) NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase)
  • dog(476754) NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase)
  • cow(338079) NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase)
  • sheep(101114702) NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase)
  • Goat(100860782) NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase)
  • naked mole-rat(101702397) NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase)

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Antibodies

Product Number
Descripción
Reactividad de especies
Aplicación
Monoclonal Anti-NDUFS7, (C-terminal) antibody produced in mouse, clone 3A3, purified immunoglobulin, buffered aqueous solution,
Reactividad de especies
human
Aplicación
ELISA
Anti-NDUFS7 antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human, mouse, rat
Aplicación
ELISA
immunohistochemistry

Small Molecule - Inhibitor

Product Number
Descripción
Especie
1,1-Dimetilbiguanida hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material,
Especie
human
Metformina hydrochloride, United States Pharmacopeia (USP) Reference Standard,
Especie
human
1,1-Dimetilbiguanida hydrochloride, 97%,
Especie
human
1,1-Dimetilbiguanida hydrochloride, European Pharmacopoeia (EP) Reference Standard,
Especie
human
Metformin hydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®,
Especie
human

esiRNA

Product Number
Descripción
Especie
MISSION® esiRNA, targeting mouse Ndufs7,
Especie
mouse
MISSION® esiRNA, targeting human NDUFS7,
Especie
human