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Merck

PRKCB

protein kinase C, beta

Sinónimos:
PKC-beta, PKCB, PRKCB1, PRKCB2
Especie:
ID UniProtKB:
ID del gen:
  • Human(5579) Summary: Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This protein kinase has been reported to be involved in many different cellular functions, such as B cell activation, apoptosis induction, endothelial cell proliferation, and intestinal sugar absorption. Studies in mice also suggest that this kinase may also regulate neuronal functions and correlate fear-induced conflict behavior after stress. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
  • Mouse(18751) protein kinase C, beta
  • Rat(25023) protein kinase C, beta
  • Domestic Rabbit(100037719) protein kinase C, beta
  • sheep(101118410) protein kinase C, beta
  • naked mole-rat(101722702) protein kinase C, beta
  • domestic cat(101088970) protein kinase C, beta
  • chicken(416567) protein kinase C, beta
  • dog(489968) protein kinase C, beta
  • cow(282325) protein kinase C, beta

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Small Molecule - Agonist

Product Number
Descripción
Especie
Ácido oleico, ≥99% (GC),
Especie
human

Antibodies

Product Number
Descripción
Reactividad de especies
Aplicación
Anti-PRKCB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence
immunohistochemistry
Anti-p-PKCβ (Ser660) Antibody, clone 2C11 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
bovine, human, monkey, mouse, rabbit, rat
Aplicación
affinity binding assay
immunocytochemistry

inhibition assay

western blot
Anti-PKCβ Antibody, clone 2E13 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
human, monkey, mouse
Aplicación
affinity binding assay
immunocytochemistry

immunohistochemistry

western blot
Anti-PRKCB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reactividad de especies
human
Aplicación
immunofluorescence
ANTI-PKC BETA1/2 (CENTER) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
western blot

Small Molecule - Inhibitor

Product Number
Descripción
Especie
Hispidin, solid, ≥98% (HPLC),
Especie
human
H-7 dihydrochloride, ≥98% (HPLC),
Especie
human
Tamoxifen citrate salt, ≥99%,
Especie
human
Ácido oleico, ≥99% (GC),
Especie
human
UCN-01, ≥97% (HPLC), powder,
Especie
human

Proteins

Product Number
Descripción
Especie
Protein kinase CβII isozyme human, >85% (SDS-PAGE), recombinant, expressed in baculovirus infected insect cells, buffered aqueous glycerol solution,
Especie
human

esiRNA

Product Number
Descripción
Especie
MISSION® esiRNA, targeting mouse Prkcb,
Especie
mouse
MISSION® esiRNA, targeting human PRKCB,
Especie
human