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Merck

11590

4,4′-Azobis(4-cyanovaleric acid)

≥98.0% (T)

Sinónimos:

4,4′-Azobis(4-cyanopentanoic acid), ABCVA, ACVA

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Fórmula lineal:
HOCOCH2CH2C(CH3)(CN)N=NC(CH3)(CN)CH2CH2COOH
Número CAS:
Peso molecular:
280.28
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
220-135-0
Beilstein/REAXYS Number:
1729856
MDL number:
Assay:
≥98.0% (T)
Form:
solid
Servicio técnico
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Quality Level

assay

≥98.0% (T)

form

solid

impurities

≤1% water

mp

118-125 °C (dec.) (lit.)

functional group

azo, carboxylic acid, nitrile

storage temp.

2-8°C

SMILES string

CC(CCC(O)=O)(\N=N\C(C)(CCC(O)=O)C#N)C#N

InChI

1S/C12H16N4O4/c1-11(7-13,5-3-9(17)18)15-16-12(2,8-14)6-4-10(19)20/h3-6H2,1-2H3,(H,17,18)(H,19,20)/b16-15+

InChI key

VFXXTYGQYWRHJP-FOCLMDBBSA-N

Application

4,4′-Azobis(4-cyanovaleric acid) has been used in the preparation of polystyrene particles by polymerizing styrene in ethyl alcohol.

Biochem/physiol Actions

4,4′-azobis(4-cyanovaleric acid) is an azo-initiator that induces lipid peroxidation of sunflower oil.


pictograms

Flame

signalword

Danger

hcodes

Hazard Classifications

Self-react. D

Clase de almacenamiento

5.2 - Organic peroxides and self-reacting hazardous materials

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges



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Ray Chang et al.
Polymers, 10(10) (2019-04-10)
Temperature stimulus, easy modulation in comparison to other environmental stimuli, makes thermo-responsive nanocarriers popular in the applications of controlled drug release for cancer therapy. In this study, photosensitive sodium copper chlorophyllin (SCC) was incorporated into thermo-responsive polymeric nanogels consisted of
B Pekiner et al.
Biochemistry and molecular biology international, 33(6), 1159-1167 (1994-08-01)
Haemolysis induced by a free radical initiator (4,4'azobis-(4-cyanovaleric acid) has been studied with transfusion blood. Azobis cyanovaleric acid caused an increase in haemolysis. The effect of alpha- and gamma-tocopherol, 2,2,5,7,8 pentamethyl-6-chromanol and 2,2,7,8 tetramethyl-6-chromanol on the red blood cell haemolysis
Eric D Nelson et al.
Journal of pharmaceutical sciences, 95(7), 1527-1539 (2006-05-26)
AIBN and ACVA oxidative forced degradation models are examined for two drug molecules whose predominant oxidation chemistries arise from different reaction mechanisms (i.e., free radical vs. nucleophilic). Stress was conducted under a variety of initiator concentrations, and under ambient and