Azidotrimethylsilane

Azidotrimethylsilane (TMSN₃) is a a colorless and stable organosilane reagent. It shows very slow decomposition at high temperatures. It is a very commonly used azide source and has been used in the synthesis of aminotriazole ligands. Azidotrimethylsilane can be easily synthesised by adding chlorotrimethylsilane dropwise to a stirred solution of NaN₃ in diethylene glycol dimethyl ether.

Azidotrimethylsilane can be used as:

• A nitrogen precursor to prepare GaN nanowire via metal-organic chemical vapor deposition method.
• An electrolyte additive in Li-O₂ batteries. The addition of TMSN₃ results in the formation of robust solid electrolyte interphase.
• An efficient reagent in the synthesis of tetrazoles, fullerenyl azide, and α-azido oximes.
• A silylating agent in the O-trimethyl silylation of alcohols and phenols.