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Merck

810187P

Avanti

TopFluor PI

Avanti Research - A Croda Brand

Sinónimos:

1-oleoyl-2-{6-[4-(dipyrrometheneboron difluoride)butanoyl]amino}hexanoyl-sn-glycero-3-phosphoinositol (ammonium salt)

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Fórmula empírica (notación de Hill):
C50H84BF2N4O14P
Número CAS:
Peso molecular:
1045.00
MDL number:
NACRES:
NA.25
UNSPSC Code:
12352211
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Nombre del producto

TopFluor PI, Avanti Research - A Croda Brand 810187P, powder

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 50 μg (with stopper and crimp cap (810187P-50ug))

manufacturer/tradename

Avanti Research - A Croda Brand 810187P

shipped in

dry ice

storage temp.

−20°C

General description

Phosphatidylinositol (PI) is commonly found in animal tissues and bacteria. PI is soluble in water and chloroform/methanol.

Application

TopFluor PI or 1-oleoyl-2-{6-[4-(dipyrrometheneboron difluoride)butanoyl]amino}hexanoyl-sn-glycero-3-phosphoinositol (ammonium salt) has been used as a fluorescent lipid in living cells to analyse the cellular localization of phosphatidylinositol (PI).

Packaging

2 mL Amber Serum Vial with Stopper and Crimp Cap (810187P-50ug)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC
TopFluor is a trademark of Avanti Polar Lipids, LLC


Clase de almacenamiento

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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Lipids of membranes: Chemistry, biological role and applications as drug carriers
Hatziantonioy S and Demetzos C
Studies in Natural Products Chemistry, 34, 173-202 (2009)
Probing the subcellular distribution of phosphatidylinositol reveals a surprising lack at the plasma membrane.
James PZ, et al.
The Journal of Cell Biology, 219(3), e201906127-e201906127 (2020)
James P Zewe et al.
The Journal of cell biology, 219(3) (2020-03-27)
The polyphosphoinositides (PPIn) are central regulatory lipids that direct membrane function in eukaryotic cells. Understanding how their synthesis is regulated is crucial to revealing these lipids' role in health and disease. PPIn are derived from the major structural lipid, phosphatidylinositol