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Merck

05-938

Anti-ORC6 Antibody, clone 3A4

clone 3A4, Upstate®, from rat

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UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
3A4, monoclonal
Application:
ChIP, WB
Citations:
4
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biological source

rat

Quality Level

conjugate

unconjugated

antibody form

purified antibody

antibody product type

primary antibodies

clone

3A4, monoclonal

species reactivity

human

manufacturer/tradename

Upstate®

technique(s)

ChIP: suitable, western blot: suitable

isotype

IgG2a

NCBI accession no.

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... ORC6(23594)

General description

30kDa A non specific protein was also detected at Mr 120kDa

Immunogen

Full-length human origin recognition complex 6 (ORC6). Clone 3A4.

Application

Anti-ORC6 Antibody, clone 3A4 is a high quality Rat Monoclonal Antibody for the detection of ORC6 & has been validated in ChIP & WB.

Biochem/physiol Actions

ORC6

Physical form

Format: Purified

Analysis Note

Control
Positive Antigen Control: Catalog #12-309, Hela cell nuclear extract. Add an equal volume of Laemmli reducing sample buffer to 10 μL of extract and boil for 5 minutes to reduce the preparation. Load 20 μg of reduced extract per lane for minigels.
Routinely evaluated by immunoblot.

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany


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Clase de almacenamiento

12 - Non Combustible Liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable



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Aparna Palakodeti et al.
Human molecular genetics, 19(1), 99-110 (2009-10-10)
Chromosomal common fragile sites (CFSs) are genetically unstable regions of the genome that are induced by conditions that impair DNA replication. In this report, we show that treatment with the DNA polymerase inhibitor, aphidicolin (APH), slows the replication rate throughout
Complex protein-DNA dynamics at the latent origin of DNA replication of Epstein-Barr virus.
Ritzi, Marion, et al.
Journal of Cell Science, 116, 3971-3984 (2003)
Isabelle Lucas et al.
EMBO reports, 8(8), 770-777 (2007-08-02)
Mapping origins of replication has been challenging in higher eukaryotes. We have developed a rapid, genome-wide method to map origins of replication in asynchronous human cells by combining the nascent strand abundance assay with a highly tiled microarray platform, and



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SKUGTIN
05-93804053252671579