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Documentos clave

COA/COQ

06-1102

Anti-Protein patched homolog 1 Antibody

Name: Anti-Protein patched homolog 1 Antibody
Brand: MM

from rabbit, purified by affinity chromatography

Sinónimos:

PTCH protein +12b, PTCH protein +4′, PTCH protein -10, patched (Drosophila) homolog, patched homolog (Drosophila), patched homolog 1 (Drosophila)

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About This Item

Código UNSPSC:

12352203

eCl@ss:

32160702

NACRES:

NA.41

origen biológico

rabbit

Nivel de calidad

100

conjugado

unconjugated

forma del anticuerpo

affinity isolated antibody

tipo de anticuerpo

primary antibodies

clon

polyclonal

purificado por

affinity chromatography

reactividad de especies

mouse, human

técnicas

immunohistochemistry: suitable
western blot: suitable

Nº de acceso NCBI

NP_000255

Nº de acceso UniProt

Q13635

Condiciones de envío

wet ice

modificación del objetivo postraduccional

unmodified

Información sobre el gen

human ... PTCH1(5727)

Descripción general

Protein patched homolog 1 is a receptor for sonic hedgehog, a member of the hedgehog family of cell signaling proteins. Hedgehog signaling is regulated by Protein patched homolog 1 which keeps the pathway turned off in the absences of activation. This inhibits the function of associated downstream network components such as Smoothened (Smo).

Especificidad

This antibody recognizes the cytoplasmic domain of Protein patched homolog 1.

Inmunógeno

Epitope: Cytoplasmic domain

KLH-conjugated linear peptide corresponding to the cytoplasmic domain of human Protein patched homolog 1.

Aplicación

Anti-Protein patched homolog 1 Antibody detects level of Protein patched homolog 1 & has been published & validated for use in WB, IH.

Immunohistochemistry Analysis: 1:300 dilution from a previous lot detected Protein patched homolog 1 in kidney tissue.

Research Category
Signaling

Calidad

Evaluated by Western Blot in human skeletal muscle, fetal tissue lysate.

Western Blot Analysis: 0.1 µg/ml of this antibody detected Protein patched homolog 1 on 10 µg of human skeletal muscle, fetal tissue lysate.

Descripción de destino

~ 160 kDa

Forma física

Affinity purified

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.05% sodium azide.

Almacenamiento y estabilidad

Stable for 1 year at 2-8°C from date of receipt.

Nota de análisis

Control
Human skeletal muscle, fetal tissue lysate

Otras notas

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Código de clase de almacenamiento

12 - Non Combustible Liquids

Clase de riesgo para el agua (WGK)

WGK 1

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)