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p38/SAPK2 Inhibitor (SB 202190)
The p38/SAPK2 Inhibitor (SB 202190) controls the biological activity of p38/SAPK2. This small molecule/inhibitor is primarily used for Biochemicals applications.
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About This Item
Código UNSPSC:
12352200
eCl@ss:
32160405
NACRES:
NA.41
Nivel de calidad
Formulario
solid
fabricante / nombre comercial
Upstate®
técnicas
activity assay: suitable (kinase)
Nº de acceso NCBI
Nº de acceso UniProt
Condiciones de envío
wet ice
Aplicación
Potent inhibitor of p38 alpha/SAPK2a and p38 beta/SAPK2b kinases.
The p38/SAPK2 Inhibitor (SB 202190) controls the biological activity of p38/SAPK2. This small molecule/inhibitor is primarily used for Biochemicals applications.
Acciones bioquímicas o fisiológicas
Inhibitor Type: Kinase
Protein Target: p38/SAPK2
Target Sub-Family: CMGC
Forma física
C20H14FN3O
Nota de preparación
3 years at -20°C
Nota de análisis
Routinely evaluated in a kinase assay as an inhibitor.
Información legal
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Cláusula de descargo de responsabilidad
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Código de clase de almacenamiento
11 - Combustible Solids
Clase de riesgo para el agua (WGK)
WGK 3
Punto de inflamabilidad (°F)
Not applicable
Punto de inflamabilidad (°C)
Not applicable
Certificados de análisis (COA)
Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»
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The Ca2+-sensitive 85-kDa cytosolic phospholipase A2 (cPLA2) is responsible for thrombin-stimulated mobilization of arachidonic acid for the synthesis of thromboxane A2 in human platelets. We have previously shown that thrombin activates p38 kinase, a recently discovered new member of the
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We have identified a third member of the p38 group of MAP kinase termed p38 gamma. The cDNA for this MAP kinase encodes an 367 amino acid polypeptide that is slightly greater than 60% identical to p38 and p38 beta.
J C Lee et al.
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Número de artículo de comercio global
| SKU | GTIN |
|---|---|
| 19-134 | 04053252337871 |
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