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Documentos clave

COA/COQ

ABC339

Anti-BFL-1 Antibody

Name: Anti-BFL-1 Antibody
Brand: MM

from rabbit, purified by affinity chromatography

Sinónimos:

Bcl-2-related protein A1, Bcl-2-like protein 5, Bcl2-L-5, Hemopoietic-specific early response protein, Protein BFL-1, Protein GRS, BFL-1

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About This Item

Código UNSPSC:

12352203

eCl@ss:

32160702

NACRES:

NA.41

origen biológico

rabbit

Nivel de calidad

100

conjugado

unconjugated

forma del anticuerpo

affinity isolated antibody

tipo de anticuerpo

primary antibodies

clon

polyclonal

purificado por

affinity chromatography

reactividad de especies

mouse

reactividad de especies (predicha por homología)

human (immunogen homology)

técnicas

immunofluorescence: suitable
immunohistochemistry: suitable
western blot: suitable

Nº de acceso UniProt

Q16548

Condiciones de envío

wet ice

modificación del objetivo postraduccional

unmodified

Información sobre el gen

human ... BCL2A1(597)

Descripción general

Protein BFL-1, also known as protein GRS, Bcl-2-like protein 5 (Bcl2-L-5), and Bcl-2-related protein A1 (BCL2A1), is a member of the Bcl-2 family. BFL-1 can interact with Bax and suppress apoptosis by inhibiting the release of cytochrome c and caspase-3 activation. BFL-1 is expressed in peripheral blood, spleen, bone marrow, lung, small intestine, and testis.

Especificidad

This antibody recognizes the N-terminus of BFL-1.

Inmunógeno

Epitope: N-terminus

KLH-conjugated linear peptide corresponding to the N-terminus of human BFL-1.

Aplicación

Anti-BFL-1 Antibody is a highly specific rabbit polyclonal antibody, that targets Bcl-2-related protein A1 & has been tested in western blotting, IHC & Immunofluorescence.

Immunohistochemistry Analysis: 2 µg/mL from a representative lot detected BFL-1 in mouse kidney tissue.

Immunofluorescence Analysis: 20 µg/mL from a representative lot detected BFL-1 in mouse kidney cells.

Research Category
Apoptosis & Cancer

Research Sub Category
Apoptosis - Additional

Calidad

Evaluated by Western Blotting in mouse kidney tissue lysate.

Western Blotting Analysis: 1 µg/mL of this antibody detected BFL-1 in 15 µg of mouse kidney tissue lysate.

Descripción de destino

~39 kDa observed. Uniprot describes two isoforms at ~19 kDa and ~20 kDa

Forma física

Antigen Affinity Purified

Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.

Almacenamiento y estabilidad

Stable for 1 year at 2-8°C from date of receipt.

Nota de análisis

Control
Mouse kidney tissue lysate

Otras notas

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Código de clase de almacenamiento

10 - Combustible liquids

Clase de riesgo para el agua (WGK)

WGK 2

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)