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Documentos clave

COA/COQ

ABS236

Anti-Cytochrome P450 (scc) Antibody, a.a. 509-526

Name: Anti-Cytochrome P450 (scc) Antibody, a.a. 509-526
Brand: MM

from rabbit, purified by affinity chromatography

Sinónimos:

Cholesterol side-chain cleavage enzyme, mitochondrial, CYPXIA1, Cholesterol desmolase, Cytochrome P450 11A1, Cytochrome P450(scc)

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About This Item

Código UNSPSC:

12352203

eCl@ss:

32160702

NACRES:

NA.41

origen biológico

rabbit

Nivel de calidad

100

conjugado

unconjugated

forma del anticuerpo

affinity isolated antibody

tipo de anticuerpo

primary antibodies

clon

polyclonal

purificado por

affinity chromatography

reactividad de especies

rat

técnicas

immunohistochemistry: suitable (paraffin)
western blot: suitable

Nº de acceso NCBI

NP_058982

Nº de acceso UniProt

P14137

Condiciones de envío

wet ice

modificación del objetivo postraduccional

unmodified

Información sobre el gen

rat ... Cyp11A1(29680)

Descripción general

As a member of the cytochrome P450 family, Cytochrome P450 Side Chain Cleavage Enzyme (scc) catalyzes the side-chain cleavage reaction of cholesterol to pregnenolone during the first step of steroid biosynthesis. It is expressed in certain organs, such as ovaries, adrenal glands, and testis. Deficiency in CYP11A1 is commonly associated with adrenal insufficiency, and with variable degrees of disorder of sex development (DSD).

~52 kDa observed. On higher percentage gels and longer exposures, 8 kDa cleavage product can be detected.

Inmunógeno

KLH-conjugated linear peptide corresponding to the C-terminus of rat Cytochrome P450 (scc), a.a. 509-526.

Aplicación

Immunohistochemistry Analysis: A 1:4,000-8,000 dilution from a representative lot detected Cytochrome P450 (scc) in rat adrenal gland and rat testis tissue.

This Cytochrome P450 (scc) antibody is validated for use in WB & IHC for the detection of the Cytochrome P450 (scc) protein.

Acciones bioquímicas o fisiológicas

This antibody recognizes the C-terminus of Cytochrome P450 (scc), a.a. 509-526.

Nota de análisis

Control
Rat adrenal tissue lysate

Evaluated by Western Blot in rat adrenal tissue lysate.

Western Blot Analysis: 0.02 µg/mL of this antibody detected Cytochrome P450 (scc) in 10 µg of rat adrenal tissue lysate.

Otras notas

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Replaces: AB1294

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Código de clase de almacenamiento

12 - Non Combustible Liquids

Clase de riesgo para el agua (WGK)

WGK 1

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)