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Documentos clave

COA/COQ

MABT180

Anti-MLC-2 Antibody, clone 19D3.1

Name: Anti-MLC-2 Antibody, clone 19D3.1
Brand: MM

clone 19D3.1, from mouse

Sinónimos:

Myosin regulatory light chain 2, ventricular/cardiac muscle isoform, MLC-2, MLC-2v

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About This Item

Código UNSPSC:

12352203

eCl@ss:

32160702

NACRES:

NA.41

origen biológico

mouse

Nivel de calidad

100

conjugado

unconjugated

forma del anticuerpo

purified immunoglobulin

tipo de anticuerpo

primary antibodies

clon

19D3.1, monoclonal

reactividad de especies

human, rat

técnicas

immunohistochemistry: suitable
western blot: suitable

isotipo

IgG1κ

Nº de acceso NCBI

NP_000423

Nº de acceso UniProt

P10916

Condiciones de envío

wet ice

modificación del objetivo postraduccional

unmodified

Información sobre el gen

human ... MYL2(4633)

Descripción general

Myosin light chain 2 (MLC2), also known as myosin regulatory light chain (MRLC), RLC, or LC20, has several isoforms and is a component of myosin, which is made up of two heavy chains and four light chains. MLC2 is involved in smooth muscle contraction, stress fiber assembly, and cytokinesis. MLC2 defects can cause of familial hypertrophic cardiomyopathy type 10 (CMH10).

Especificidad

Other homologies: Mouse 92% sequence homologies.

Inmunógeno

GST-tagged recombinant protein corresponding to human MLC-2.

Aplicación

Detect Myosin using this mouse monoclonal antibody, Anti-MLC-2 Antibody, clone 19D3.1 validated for use in western blotting & IHC.

Immunohistochemistry Analysis: A 1:1,000 dilution from a representative lot detected MLC-2 in human cardiac myocyte and in rat skeletal muscle tissues.

Research Category
Cell Structure

Research Sub Category
ECM Proteins

Calidad

Evaluated by Western Blotting in human skeletal muscle tissue lysate.

Western Blotting Analysis: A 1:2,000 dilution from a representative lot detected MLC-2 in 10 µg of human skeletal muscle tissue lysate.

Descripción de destino

~19 kDa observed

Forma física

Format: Purified

Protein G Purified

Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Almacenamiento y estabilidad

Stable for 1 year at 2-8°C from date of receipt.

Nota de análisis

Control
Human skeletal muscle tissue lysate.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Código de clase de almacenamiento

12 - Non Combustible Liquids

Clase de riesgo para el agua (WGK)

WGK 1

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)