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Merck

MTH17MAG-47K

Millipore

MILLIPLEX® Mouse TH17 Magnetic Bead Panel - Immunology Multiplex Assay

Simultaneously analyze multiple Th17 cytokine and chemokine biomarkers with the Th17 Bead-Based Multiplex Assays using the Luminex technology, in human serum, plasma and cell culture samples.

Sinónimos:

Luminex® Mouse Immunology Panel, Millipore Mouse Immunology Panel, Mouse Immunology Protein Multiplex Assay

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About This Item

Código UNSPSC:
12161503
eCl@ss:
32161000
NACRES:
NA.84

Nivel de calidad

reactividad de especies

mouse

fabricante / nombre comercial

Milliplex®

assay range

linearity: 111.0%
(1:04)

linearity: 113.1%
(1:08)

standard curve range: 1.5-1,500 pg/mL
(IL-4)

standard curve range: 10-10,000 pg/mL
(IL-17F)

standard curve range: 127-130,000 pg/mL
(IL-28B)

standard curve range: 15-15,000 pg/mL
(IL-1β)

standard curve range: 2.4-2,500 pg/mL
(IL-22)

standard curve range: 20-20,000 pg/mL
(IL-10, IL-12(p70), & IL-21)

standard curve range: 3.4-3,500 pg/mL
(TNFα)

standard curve range: 34-35,000 pg/mL
(GM-CSF & IL-15)

standard curve range: 342-350,000 pg/mL
(IL-23)

standard curve range: 39-40,000 pg/mL
(IL-13 & IL-17A)

standard curve range: 4.9-5,000 pg/mL
(IL-5)

standard curve range: 488-500,000 pg/mL
(TNFβ)

standard curve range: 49-50,000 pg/mL
(CD40L IL-31 & MIP-3α)

standard curve range: 586-600,000 pg/mL
(IL-17E/ IL-25)

standard curve range: 6.9-6,000 pg/mL
(IL-2)

standard curve range: 7.8-8,000 pg/mL
(IFNγ & IL-6)

standard curve range: 78-80,000 pg/mL
(IL-33)

standard curve range: 879-900,000 pg/mL
(IL-27)

técnicas

multiplexing: suitable

método de detección

fluorometric (Luminex xMAP)

Condiciones de envío

wet ice

Descripción general

The MILLIPLEX® Mouse Th17 Bead panel enables you to focus on the therapeutic potential of the modulation of CD4 T-helper cell cytokines. Coupled with the Luminex® xMAP®platform in a bead format, you receive the advantage of ideal speed and sensitivity, allowing quantitative multiplex detection of dozens of analytes simultaneously, which can dramatically improve productivity.

Panel Type: Cytokines/Chemokines

Aplicación

  • Analytes: CD40 Ligand, GM-CSF, IFN-γ, IL-1β, IL-2, IL-4, IL-5, IL-6, IL-10, IL-12 (p70), IL-13, IL-15, IL-17A, IL-17E/IL-25, IL-17F, IL-21, IL-22, IL-23, IL-27, IL-28B, IL-31, IL-33, MIP-3α/CCL20, TNF-α, TNFβ
  • Recommended Sample type: serum, plasma or tissue/cell lysate and culture supernatant
  • Recommended Sample dilution: neat
  • Assay Run Time: overnight or one day
  • Research Category: Inflammation & Immunology

Acciones bioquímicas o fisiológicas

Cross Reactivty
There was no or minimum cross-reactivity between the antibodies and any other analytes in the panel (see details in assay protocol).

Características y beneficios

Design your multiplex kit by choosing available analytes within this panel.

Nota de preparación

Recommended storage for kit components is 2 - 8°C.

Otras notas

Sensitivity: Refer to kit protocol for sensitivities of individual biomarkers.

Información legal

Luminex is a registered trademark of Luminex Corp
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Palabra de señalización

Danger

Clasificaciones de peligro

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Sens. 1 - STOT RE 2

Órganos de actuación

Respiratory Tract

Código de clase de almacenamiento

10 - Combustible liquids


Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Mohammad Afzal Khan et al.
Cells, 10(5) (2021-06-03)
Interleukin-10 plays a vital role in maintaining peripheral immunotolerance and favors a regulatory immune milieu through the suppression of T effector cells. Inflammation-induced microvascular loss has been associated with airway epithelial injury, which is a key pathological source of graft
M John Albert et al.
Scientific reports, 9(1), 12024-12024 (2019-08-21)
There is no information on cytokine profiles for use as markers of protection in Campylobacter jejuni infection. To study this, we used outer membrane protein (MOMP [PorA]) as the vaccine for protection and spleen cell cytokines as markers of protection.
Mohammad Afzal Khan et al.
Frontiers in immunology, 9, 1010-1010 (2018-06-09)
Microvascular injury during acute rejection has been associated with massive infiltration of CD4+ T effector cells, and the formation of complement products (C3a and C5a). Regulatory T cells (Tregs) are potent immunosuppressors of the adaptive immune system and have proven
Sarah J Dulson et al.
Journal of immunology (Baltimore, Md. : 1950), 203(9), 2472-2484 (2019-09-29)
Innate lymphoid cells (ILCs) are strategically positioned at mucosal barrier surfaces where they respond quickly to infection or injury. Therefore, we hypothesized that ILCs are key contributors to the early immune response in the intestine against Listeria monocytogenes Using a
Anthony Tam et al.
Cells, 11(19) (2022-10-15)
Genome-wide association studies (GWAS) have shown that variants of patched homolog 1 (PTCH1) are associated with lung function abnormalities in the general population. It has also been shown that sonic hedgehog (SHH), an important ligand for PTCH1, is upregulated in

Contenido relacionado

See how multiplexing the inflammation signaling pathway with MILLIPLEX® inflammation assays or cell signaling assays can help researchers bridge the gap between immunology and cell signaling, including investigating T cell signaling, Th Cell differentiation, inflammatory response signaling, and sepsis signaling.

Discover the benefits of MILLIPLEX® multiplex assays, based on Luminex® xMAP® multiplex assay technology, that provide consistent, high-quality results and see how these multiplex biomarker Luminex® assays are being used to advance research.

Número de artículo de comercio global

SKUGTIN
MTH17MAG-47K-0604053252799563
MTH17MAG-47K-07C04055977103052
MTH17MAG-47K-03C04055977107678
MTH17MAG-47K-23C04055977103168
MTH17MAG-47K-10C04055977103076
MTH17MAG-47K-1404053252799648
MTH17MAG-47K-20C04055977103144
MTH17MAG-47K-1704053252799679
MTH17MAG-47K-18C04055977103120
MTH17MAG-47K-2404053252799747
MTH17MAG-47K-0904053252799594
MTH17MAG-47K-0104053252799518
MTH17MAG-47K-02C04055977108644
MTH17MAG-47K-1104053252799617
MTH17MAG-47K-0204053252799525
MTH17MAG-47K-1204053252799624
MTH17MAG-47K-22C04055977103151
MTH17MAG-47K-0504053252799556
MTH17MAG-47K-19C04055977103137
MTH17MAG-47K-01C04055977103014
MTH17MAG-47K-06C04055977103045
MTH17MAG-47K-1604053252799662
MTH17MAG-47K-16C04055977103113
MTH17MAG-47K-17C04055977107708

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