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Merck

46289

Furaltadone

VETRANAL®, analytical standard

Sinónimos:

5-Morpholinomethyl-3-(5-nitrofurfurylideneamino)-2-oxazolidinone

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Fórmula empírica (notación de Hill):
C13H16N4O6
Número CAS:
Peso molecular:
324.29
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
205-384-5
Beilstein/REAXYS Number:
8130725
MDL number:
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InChI key

YVQVOQKFMFRVGR-VGOFMYFVSA-N

InChI

1S/C13H16N4O6/c18-13-16(14-7-10-1-2-12(22-10)17(19)20)9-11(23-13)8-15-3-5-21-6-4-15/h1-2,7,11H,3-6,8-9H2/b14-7+

SMILES string

[O-][N+](=O)c1ccc(\C=N\N2CC(CN3CCOCC3)OC2=O)o1

grade

analytical standard

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

clinical testing

format

neat

storage temp.

2-8°C

Quality Level

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General description

Furaltadone is a nitrofuran drug, with broad-spectrum antimicrobial activity. It is widely used in veterinary medicine for intensive animal production, especially in pigs, poultry, fish and to provide resistance against infections caused by Escherichia coli and Salmonella.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support. Furaltadone may be used as an analytical reference standard for the quantification of the analyte in milk samples and poultry eggs using different chromatography techniques.

Other Notes

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral

Clase de almacenamiento

11 - Combustible Solids

wgk

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Gloves


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Determination of nitrofurantoin, furazolidone and furaltadone in milk by high-performance liquid chromatography with electrochemical detection
Diaz G.T, et al.
Analytical Methods : Advancing Methods and Applications, 764(2), 243-248 (1997)
A Stammati et al.
Cell biology and toxicology, 13(2), 125-130 (1997-02-01)
Nitrofuran drugs have been studied on cellular systems in order to develop in vitro tests for safety assessment of food contaminants. In the present study we have tested furaltadone on three cell lines (HEp-2, Caco-2 and V79), using the same
B Murugasu-Oei et al.
The Journal of antimicrobial chemotherapy, 46(6), 917-919 (2000-12-05)
Depletion of oxygen triggers the shift-down of Mycobacterium bovis BCG to a state of dormancy. Bacilli in their dormant state are resistant to standard anti-mycobacterials. The nitroimidazole metronidazole was the first compound identified to show bactericidal activity against dormant tubercle
S Khalil et al.
Journal of pharmaceutical and biomedical analysis, 27(1-2), 117-122 (2001-10-30)
Ion-associate complexes of furaltadone, methadone and trazodone hydrochlorides with [Cd(SCN)(4)](2-) and [Zn(SCN)(4)](2-) were precipitated and the excess unreacted cadmium or zinc complex was determined. A new method using atomic emission and atomic absorption spectrometry for the determination of the above
Eric Verdon et al.
Analytica chimica acta, 586(1-2), 336-347 (2007-03-28)
Following the ban of four nitrofurans in the mid-90s (furazolidone, furaltadone, nitrofurantoine, nitrofurazone), the nifursol, a veterinary drug from the nitrofuran class of antibacterials which has been used prophylactically as feed additive for treating turkeys against histomoniasis (blackhead disease) was

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