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Merck

65692

1-Methoxy-2-propanol

greener alternative

analytical standard

Sinónimos:

Propylene glycol methyl ether, Propyleneglycol monomethyl ether

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Fórmula lineal:
CH3CH(OH)CH2OCH3
Número CAS:
107-98-2
Peso molecular:
90.12
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329760094
EC Number:
203-539-1
Beilstein/REAXYS Number:
1731270
MDL number:
MFCD00004537

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InChI key

ARXJGSRGQADJSQ-UHFFFAOYSA-N

InChI

1S/C4H10O2/c1-4(5)3-6-2/h4-5H,3H2,1-2H3

SMILES string

CC(O)COC

grade

analytical standard

vapor density

3.12 (vs air)

vapor pressure

10.9 mmHg ( 25 °C)

assay

≥99.7% (GC)

autoignition temp.

532 °F

shelf life

limited shelf life, expiry date on the label

expl. lim.

13.8 %

Quality Level

100

refractive index

n20/D 1.403

greener alternative product characteristics

Safer Solvents and Auxiliaries
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

bp

118-119 °C (lit.)

density

0.916 g/mL at 25 °C (lit.)

application(s)

environmental

format

neat

greener alternative category

Aligned

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General description

1-Methoxy-2-propanol is one of the most common propylene-based glycol ethers that find potential use in several industrial and commercial applications, major use being as a component of paints, varnishes, inks, etc. It is often utilized as a less potent substitute for short-chained ethylene glycol ethers.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
1-Methoxy-2-propanol may be used as an analytical standard for the determination of the analyte in human and animal biological samples by various chromatography techniques.

Features and Benefits

We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Green Chemistry. Monoethers, especially propylene glycol methyl ether (PGME), are widely used as pollution-free solvents in fine chemical synthesis in pharmaceutical, chemical and cosmetic industries and thus aligns with "Safer Solvents and Auxiliaries". Click here for more information.

pictograms

FlameExclamation mark
GHS02,GHS07

signalword

Warning

hcodes

H226,H336

Hazard Classifications

Flam. Liq. 3 - STOT SE 3

target_organs

Central nervous system

Clase de almacenamiento

3 - Flammable liquids

wgk

WGK 1

flash_point_f

93.2 °F - closed cup

flash_point_c

34 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

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Certificados de análisis (COA)

Lot/Batch Number
BCCM6195
BCCK6589
BCCD8085
BCBX4461
BCBR2420V

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J Laitinen et al.
Journal of chromatography. B, Biomedical sciences and applications, 694(1), 93-98 (1997-06-20)
At the end of a workweek 23 silkscreen printers gave a urine sample for capillary gas chromatographic analysis for 1,2-propanediol. The mean concentration was 2.52 (S.D. 2.01) mmol mol creatinine(-1) (median=1.76, n=23). The urinary excretion of 1,2-propanediol was linearly dependent
A biological monitoring study of 1-methoxy-2-propanol: analytical method development and a human volunteer study
Jones K, et al.
The Science of the Total Environment, 199(1-2), 23-30 (1997)
Gas-chromatographic determination of propylene-and diethylene glycol ethers in urine
Hubner B, et al.
Fresenius Journal of Analytical Chemistry, 342(9), 746-748 (1992)
N F Ferrala et al.
Journal of chromatography. B, Biomedical applications, 660(2), 291-296 (1994-10-14)
A method utilizing capillary GC and flame ionization detection was developed for the simultaneous determination of 1-methoxy-2-propanol (propylene glycol monomethyl ether; PGME) and its metabolite 1,2-propanediol (propylene glycol; PG) in rat and mouse plasma. The calibration graphs for rat and
Catherine Tomicic et al.
Analytical and bioanalytical chemistry, 396(7), 2709-2714 (2010-02-16)
Glycol ethers still continue to be a workplace hazard due to their important use on an industrial scale. Currently, chronic occupational exposures to low levels of xenobiotics become increasingly relevant. Thus, sensitive analytical methods for detecting biomarkers of exposure are
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