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non-ionic
Quality Level
form
viscous liquid
mol wt
~603
CMC
0.08 mM (20-25°C)
viscosity
250-350 cP, neat(25 °C)(lit.)
density
1.06 g/cm3 at 25 °C (lit.)
HLB
13
SMILES string
O(CCO)c1ccc(cc1)C(CC(C)(C)C)(C)C
InChI
1S/C16H26O2/c1-15(2,3)12-16(4,5)13-6-8-14(9-7-13)18-11-10-17/h6-9,17H,10-12H2,1-5H3
InChI key
JYCQQPHGFMYQCF-UHFFFAOYSA-N
General description
IGEPAL® CA-630 is a nonionic, non-denaturing detergent suitable for solubilization, isolation and purification of membrane protein complexes. It is chemically indistinguishable from Nonidet P-40.
Application
IGEPAL® CA-630 has been used:
- as a component of grinding buffer along with lithium dodecyl sulphate, tris-HCl, EDTA, NaCl, sodium deoxycholate, dithiothreitol and thiourea in RNA extraction process
- along with Tris- HCl in incubation of Tachyzoites cultured in vero cells
- as a component of nuclear extract buffer D+ containing HEPES, glycerol, KCl and EDTA for gel shift analysis
- as a component of PI buffer along with NaH2PO4 to wash slides in FISH (fluorescence in situ hybridization) procedure
- for solubilizing and isolation of membrane proteins
Analysis Note
Chemically indistinguishable from Nonidet P-40, which is no longer commercially available.
Other Notes
Nonionic, non-denaturing detergent
Legal Information
IGEPAL is a registered trademark of Solvay
Disclaimer
May develop turbidity or sediment during storage. A clear liquid can be obtained on heating to 40°C.
signalword
Danger
Clase de almacenamiento
10 - Combustible liquids
wgk
WGK 2
flash_point_f
483.8 °F - closed cup
flash_point_c
251 °C - closed cup
ppe
Eyeshields, Gloves, type ABEK (EN14387) respirator filter
Hazard Classifications
Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - ED ENV 1 - Eye Dam. 1 - Skin Irrit. 2
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