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M9140

Methylene blue

Dye content, ≥82%, certified by the Biological Stain Commission, powder

Sinónimos:

Basic Blue 9, 3,7-bis(Dimethylamino)phenazathionium chloride, Tetramethylthionine chloride

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Fórmula empírica (notación de Hill):
C16H18ClN3S · xH2O
Número CAS:
122965-43-9
Peso molecular:
319.85 (anhydrous basis)
UNSPSC Code:
12171500
NACRES:
NA.47
PubChem Substance ID:
24897317
EC Number:
200-515-2
MDL number:
MFCD00150006
Colour Index Number:
52015
Beilstein/REAXYS Number:
3599847
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Nombre del producto

Methylene blue, certified by the BSC

agency

certified by the BSC

Quality Level

200

form

powder

composition

Dye content, ≥82%

technique(s)

microbe id | staining: suitable

color

dark green

solubility

H2O: 4mg/4ml

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

SMILES string

CN(C)C1=CC=C2C(SC(C3=N2)=CC(C=C3)=[N+](C)C)=C1.[H]O[H].[Cl-]

InChI

1S/C16H18N3S.ClH.H2O/c1-18(2)11-5-7-13-15(9-11)20-16-10-12(19(3)4)6-8-14(16)17-13;;/h5-10H,1-4H3;1H;1H2/q+1;;/p-1

InChI key

WQVSELLRAGBDLX-UHFFFAOYSA-M

Gene Information

human ... CYP1A2(1544), GSR(2936)

General description

Methylene blue is a compound that occurs as crystals or crystalline powder, having a bronze-like luster. It is soluble in water, chloroform and partially soluble in alcohol. It is a photoactive dye, which is a member of phenothiazine family.

Application

Methylene blue has been used:
  • to stain vaginal cells
  • for the preparation of protein aqueous ink
  • to evaluate cell survival by staining

Certified for use in Mallory′s phloxine-methylene blue stain; Levine & Black stain for bacteria in milk; Wright stain for blood smears.

Biochem/physiol Actions

Methylene blue is used as a bacteriologic stain or dye and indicator. It mediates the inactivation of enveloped viruses in plasma, when exposed to visible light. It is an inhibitor of nitric oxide synthase and guanylate cyclase. It also plays a key role in medicine as an antimalarial agent, reducing agent in methemoglobinemia and inducer of apoptosis in cancer cells.

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pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302

Hazard Classifications

Acute Tox. 4 Oral

Clase de almacenamiento

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificados de análisis (COA)

Lot/Batch Number
0000532191
0000532191
SHBT4008
0000518372
0000518372

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