PHR1093
Sulfanilamide
Pharmaceutical Secondary Standard; Certified Reference Material
Sinónimos:
Sulfanilamide, p-Aminobenzenesulfonamide
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Fórmula lineal:
H2NC6H4SO2NH2
Número CAS:
Peso molecular:
172.20
NACRES:
NA.24
PubChem Substance ID:
eCl@ss:
39093202
UNSPSC Code:
41116107
EC Number:
200-563-4
MDL number:
Beilstein/REAXYS Number:
511852
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Permítanos ayudarleInChI key
FDDDEECHVMSUSB-UHFFFAOYSA-N
InChI
1S/C6H8N2O2S/c7-5-1-3-6(4-2-5)11(8,9)10/h1-4H,7H2,(H2,8,9,10)
SMILES string
Nc1ccc(cc1)S(N)(=O)=O
grade
certified reference material, pharmaceutical secondary standard
agency
traceable to USP 1633007
API family
sulfanilamide
CofA
current certificate can be downloaded
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
mp
~Approximately 166 °C
Quality Level
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
2-30°C
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General description
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Sulfanilamide Melting Point Standard, also called Sulfanilamide, is an antibacterial drug. It blocks the synthesis of dihydrofolic acid by inhibiting the enzyme dihydropteroate synthase.
Sulfanilamide Melting Point Standard also called Sulfanilamide is an antibacterial drug.
Application
It was used in a study to demonstrate photodecomposition in aqueous solution of cutaneous photosensitizing agents with the help of spin traps 5, 5-dimethyl-1-pyrroline-1-oxide.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Analysis Note
These secondary standards offer multi-traceability to the USP and EP (PhEur) primary standards, where they are available.
Other Notes
Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAB1410 in the slot below. This is an example certificate only and may not be the lot that you receive.
Clase de almacenamiento
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificados de análisis (COA)
Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»
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Encuentre la documentación para los productos que ha comprado recientemente en la Biblioteca de documentos.
SPECTROSCOPIC STUDIES OF CUTANEOUS PHOTOSENSITIZING AGENTS?II. SPIN TRAPPING OF PHOTOLYSIS PRODUCTS FROM SULFANILAMIDE AND 4-AMINOBENZOIC ACID USING 5, 5-DIMETHYL-1-PYRROLINE-1-OXIDE.
Chignell, Colin F., et al.
Photochemistry and Photobiology, 34.2 , 147-156 (1981)
Sevgi Kolayli et al.
Journal of enzyme inhibition and medicinal chemistry, 26(6), 895-900 (2011-03-09)
An α-carbonic anhydrase (CA, EC 4.2.1.1) was purified and characterized kinetically from erythrocytes of the sturgeon Acipenser gueldenstaedti, an endangered species. The sturgeon enzyme (AgCA) showed kinetic parameters for the CO(2) hydration reaction comparable with those of the human erythrocytes
Penghua Wang et al.
Water research, 45(16), 5015-5026 (2011-08-02)
A novel carbon-sensitized and nitrogen-doped TiO2 (C/N-TiO2) was synthesized by a facile sol-gel method using titanium butoxide as both titanium precursor and carbon source, and nitric acid as nitrogen source. The calcination temperature had a great effect on the crystal
Fei Liu et al.
Organic letters, 12(4), 868-871 (2010-01-19)
The synthesis of benzofused sultams and/or fluorinated sulfonamides, starting from N-allylic sulfonamides, was performed in superacid HF/SbF(5), through superelectrophilic activation. A dramatic effect of superacid composition on the selectivity of the reaction was shown and applied to the synthesis of
Ramazan Demirdağ et al.
Bioorganic & medicinal chemistry, 21(6), 1522-1525 (2012-09-15)
Carbonic anhydrase (CA, EC: 4.2.1.1) was purified from sheep kidney by affinity chromatography on a Sepharose 4B-tyrosine-sulfanilamide column. By means of two consecutive procedures, the enzyme (sCA) was purified 227.61-fold with a yield of 60.75%, and a specific activity of
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