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Fórmula lineal:
NaF
Número CAS:
Peso molecular:
41.99
NACRES:
NA.25
PubChem Substance ID:
UNSPSC Code:
12352302
EC Number:
231-667-8
MDL number:
Assay:
≥99%
Solubility:
H2O: 1 M, clear, colorless
Servicio técnico
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Permítanos ayudarlevapor pressure
1.4 mmHg ( 0 °C)
Quality Level
product line
BioXtra
assay
≥99%
impurities
≤0.0005% Phosphorus (P), ≤0.1% Insoluble matter
mp
993 °C (lit.)
solubility
H2O: 1 M, clear, colorless
anion traces
chloride (Cl-): ≤0.005%, sulfate (SO42-): ≤0.03%
cation traces
Al: ≤0.001%, Ca: ≤0.0005%, Cu: ≤0.0005%, Fe: ≤0.003%, K: ≤0.02%, Mg: ≤0.0005%, NH4+: ≤0.1%, Pb: ≤0.001%, Zn: ≤0.0005%
SMILES string
[F-].[Na+]
InChI
1S/FH.Na/h1H;/q;+1/p-1
InChI key
PUZPDOWCWNUUKD-UHFFFAOYSA-M
Application
Sodium fluoride has been used:
- as a source of fluoride ions, to analyse its impact on spermatogenesis and capacitation in vitro
- as an additive in the extraction buffer for the isolation of nuclei, cytoplasmic and nuclear proteins
- as a component of lysis buffer for the lysis of human ovarian adenocarcinoma OVCAR3 cells
Biochem/physiol Actions
Sodium fluoride (NaF) prevents dental caries, by catalysing the diffusion of calcium and phosphate and remineralizes the lesions. Fluoride affects spermatogenesis and capacitation process in the female reproductive tract. Fluoride induces oxidative stress, DNA damage in ovary ultimately affects the development of oocytes. Fluoride supplementation enhances bone mineral density. 18F-NaF is a radiotracer used in positron emission tomography (PET) to identify atherosclerotic lesions and other cardiac plaques.
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2
supp_hazards
Clase de almacenamiento
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
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Mangiferin induces apoptosis in human ovarian adenocarcinoma OVCAR3 cells via the regulation of Notch3
Zou B, et al.
Oncology Reports, 38(3), 1431-1441 (2017)
Dental caries
Selwitz RH, et al.
Lancet, 369(9555), 51-59 (2007)
Fluoride-induced oxidative stress and apoptosis are involved in the reducing of oocytes development potential in mice
Wang HW, et al.
Chemosphere, 186, 911-918 (2017)
