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Merck

M3634

Manganese(II) chloride tetrahydrate

ReagentPlus®, ≥99%

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Fórmula lineal:
MnCl2 · 4H2O
Número CAS:
Peso molecular:
197.91
NACRES:
NA.21
PubChem Substance ID:
UNSPSC Code:
12352302
EC Number:
231-869-6
MDL number:
Assay:
≥99%
Form:
powder
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InChI key

CNFDGXZLMLFIJV-UHFFFAOYSA-L

InChI

1S/2ClH.Mn.4H2O/h2*1H;;4*1H2/q;;+2;;;;/p-2

SMILES string

Cl[Mn]Cl.[H]O[H].[H]O[H].[H]O[H].[H]O[H]

product line

ReagentPlus®

assay

≥99%

form

powder

pH

3.5-6 (25 °C, 50 g/L)

mp

58 °C (lit.)

Quality Level

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General description

Manganese(II) chloride tetrahydrate is the tetrahydrate form of manganese(II) chloride. It is used in the preparation of manganese-based hybrid compounds.

Application

Manganese(II) chloride tetrahydrate can be used:      
  • As a promoter to synthesize dihydropyrimidin-2(1H)-ones by the condensation of aldehyde, β-dicarbonyl compounds, and urea under microwave conditions.      
  • As a catalyst to synthesize dihydro-2-oxypyrrole derivatives via one-pot four-component domino condensation of dialkyl acetylenedicarboxylate, formaldehyde, and amines.     
  • To synthesize active manganese oxide with potential application as an oxidant in organic synthesis.

Legal Information

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

signalword

Danger

Hazard Classifications

Acute Tox. 3 Oral - Eye Dam. 1 - STOT RE 2

target_organs

Brain

Clase de almacenamiento

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk

WGK 2

flash_point_f

does not flash

flash_point_c

does not flash


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The aim of this study was to provide data on the dose dependence of manganese-enhanced MRI (MEMRI) in the visual pathway of experimental rats and to study the toxicity of MnCl₂ to the retina. Sprague-Dawley rats were intravitreally injected with
Geoffrey J Topping et al.
Medical physics, 40(4), 042502-042502 (2013-04-06)
Manganese(II) is employed as a contrast agent with magnetic resonance imaging (MRI) for study of neuronal activation in rats and mice. However, at the concentrations required for MRI, Mn may induce pharmacological or toxic effects. Positron emission tomography (PET) imaging
Tameshwar Ganesh et al.
Journal of magnetic resonance imaging : JMRI, 41(3), 806-813 (2014-03-05)
To investigate the potential of manganese (Mn)-enhanced MRI for sensitive detection and delineation of tumors that demonstrate little enhancement on Gd-DTPA. Eighteen nude rats bearing 1 to 2 cm in diameter orthotopic breast tumors (ZR75 and LM2) were imaged on
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