63705
Sodium 2-mercaptoethanesulfonate
BioXtra, ≥98.0% (RT)
Sinónimos:
2-Mercaptoethanesulfonic acid sodium salt, Coenzyme M sodium salt, HS-CoM Na, MESNA
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Fórmula lineal:
HSCH2CH2SO3Na
Número CAS:
Peso molecular:
164.18
UNSPSC Code:
12161504
NACRES:
NA.25
PubChem Substance ID:
EC Number:
243-285-9
Beilstein/REAXYS Number:
3657828
MDL number:
Assay:
≥98.0% (RT)
Quality level:
Servicio técnico
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Permítanos ayudarleproduct line
BioXtra
Quality Level
assay
≥98.0% (RT)
loss
≤2.0% loss on drying, 20 °C (HV)
cation traces
Ca: ≤150 mg/kg, Cd: ≤5 mg/kg, Co: ≤5 mg/kg, Cr: ≤5 mg/kg, Cu: ≤5 mg/kg, Fe: ≤5 mg/kg, K: ≤100 mg/kg, Mg: ≤5 mg/kg, Mn: ≤5 mg/kg, Ni: ≤5 mg/kg, Pb: ≤5 mg/kg, Zn: ≤5 mg/kg
SMILES string
[Na+].[O-]S(=O)(=O)CCS
InChI
1S/C2H6O3S2.Na/c3-7(4,5)2-1-6;/h6H,1-2H2,(H,3,4,5);/q;+1/p-1
InChI key
XOGTZOOQQBDUSI-UHFFFAOYSA-M
Application
2-Mercaptoethanesulfonic acid sodium salt (Coenzyme M sodium salt, MESNA) is used as an antioxidant and cytoprotective agent in a wide variety of applications from protection from toxicity of therapeutic agents, such as cyclophosphamide to prevention from brain injury damage.
Other Notes
Biosynthesis of coenzyme M
Biosynthesis of coenzyme Mcitation
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Clase de almacenamiento
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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R.H. White
Biochemistry, 24, 6487-6487 (1985)
Janelle B Perkins et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 17(24), 7743-7753 (2011-10-27)
To determine the maximum tolerated dose (MTD) of topotecan in combination with ifosfamide, mesna, and etoposide (TIME), followed by autologous hematopoietic cell transplant (HCT), in patients with chemotherapy-refractory malignancies. Patients were treated with (in mg/m(2)/d) ifosfamide 3,333, mesna 3,333, and
Jun-ichi Nishigaki et al.
Inorganic chemistry, 51(6), 3690-3697 (2012-03-10)
Divalent and trivalent nickel complexes of 1,4,8,11-tetraazacyclotetradecane, denoted as cyclam hereafter, coordinated by methyl coenzyme M (MeSCoM(-)) and coenzyme M (HSCoM(-)) have been synthesized in the course our model studies of methyl coenzyme M reductase (MCR). The divalent nickel complexes