A8351
Ampicilina sodium salt
BioXtra, suitable for cell culture
Sinónimos:
D-(−)-α-Aminobencilpenicilina sodium salt
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Fórmula empírica (notación de Hill):
C16H18N3NaO4S
Número CAS:
Peso molecular:
371.39
UNSPSC Code:
51281716
NACRES:
NA.76
PubChem Substance ID:
EC Number:
200-708-1
Beilstein/REAXYS Number:
4119211
MDL number:
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Permítanos ayudarleSMILES string
[Na+].CC1(C)SC2[C@H](NC(=O)[C@H](N)c3ccccc3)C(=O)N2[C@H]1C([O-])=O
product line
BioXtra
form
powder
technique(s)
cell culture | mammalian: suitable
impurities
endotoxin, tested
color
white to off-white
mp
215 °C (dec.) (lit.)
antibiotic activity spectrum
Gram-negative bacteria, Gram-positive bacteria
mode of action
cell wall synthesis | interferes
storage temp.
2-8°C
Quality Level
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General description
Chemical structure: β-lactam
Application
Ampicillin is a semi-synthetic derivative of penicillin that functions as a broad-spectrum antibiotic. It has been used to study antibiotic resistance and penetration limitations, the synergy between multiple antibiotics, certain bloodstream infections, and has been used to develop PCR assays to detect resistance genes in cerebrospinal fluid.
Biochem/physiol Actions
Modo de acción: Es un antibiótico β-lactámico que inhibe la síntesis de la pared celular bacteriana al inactivar las transpeptidasas de la superficie interna de la membrana celular de la bacteria.
Modo de resistencia: La administración con β-lactamasa rompe el anillo β-lactámico de la ampicilina y la inactiva.
Espectro antimicrobiano: Incluye bacterias grampositivas (como la bencilpenicilina) y baterías gramnegativas (como las tetraciclinas y el cloranfenicol).
Modo de resistencia: La administración con β-lactamasa rompe el anillo β-lactámico de la ampicilina y la inactiva.
Espectro antimicrobiano: Incluye bacterias grampositivas (como la bencilpenicilina) y baterías gramnegativas (como las tetraciclinas y el cloranfenicol).
Preparation Note
Ampicillin is reported as slightly soluble in water, practically insoluble in alcohol, chloroform, ether and fixed oils but soluble in dilute acids or bases. The solution should not be autoclaved; a stock solution should be sterilized through filtration and stored frozen, where it will be stable for months.
Other Notes
Keep container tightly closed in a dry and well-ventilated place, hygroscopic.
Disclaimer
This product has been reported stable as supplied at 25°C at 43% and 81% relative humidity for six weeks. Additional studies have shown that the stability of Ampicillin in solution is a function of pH, temperature and the identity of the buffer. It′s activity is quickly lost when stored above pH 7. Optimal storage conditions are suggested as 2-8°C, and pH 3.8-5 where its activity was retained at 90%+ for a week.
signalword
Danger
hcodes
Hazard Classifications
Resp. Sens. 1A - Skin Sens. 1A
Clase de almacenamiento
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
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