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Merck

B1125

Bathocuproinedisulfonic acid disodium salt

7.2-9.1% purity dry basis (ICP), powder

Sinónimos:

2,9-Dimethyl-4,7-diphenyl-1,10-phenantrolinedisulfonic acid disodium salt, Disodium bathocuproinedisulfonate

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About This Item

Fórmula empírica (notación de Hill):
C26H18N2Na2O6S2
Número CAS:
52698-84-7
Peso molecular:
564.54
MDL number:
MFCD00011679
UNSPSC Code:
12171500
NACRES:
NA.47

Nombre del producto

Bathocuproinedisulfonic acid disodium salt, for spectrophotometric det. of Cu, Fe

SMILES string

[Na+].[Na+].[S](=O)(=O)([O-])c1c(nc2c3nc(c(c(c3ccc2c1c5ccccc5)c4ccccc4)[S](=O)(=O)[O-])C)C

InChI

1S/C26H20N2O6S2.2Na/c1-15-25(35(29,30)31)21(17-9-5-3-6-10-17)19-13-14-20-22(18-11-7-4-8-12-18)26(36(32,33)34)16(2)28-24(20)23(19)27-15;;/h3-14H,1-2H3,(H,29,30,31)(H,32,33,34);;/q;2*+1/p-2

InChI key

RNGKZLRAVYPLJC-UHFFFAOYSA-L

assay

7.2-9.1% dry basis (ICP)

form

powder

quality

for spectrophotometric det. of Cu, Fe

technique(s)

titration: 90% using HCLO4 (Dry Basis)

color

white to beige

solubility

H2O: 50 mg/mL

suitability

suitable for determination of copper

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

Quality Level

200

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Application

  • Bathocuproinedisulfonic acid disodium salt has been used as a copper chelator for specific assay in Arabidopsis seedlings.
  • It has been used as an electron chain-associated free radical production inhibitor for superoxide dismutase assay in cells.
  • It has been added to the culture media of trypanosomes as a copper chelator for the stabilization of cysteine.

General description

Bathocuproinedisulfonic acid is a strong copper chelator. It is used for the determination of copper and iron in biological samples.

Other Notes

Mixture of isomers

Clase de almacenamiento

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificados de análisis (COA)

Lot/Batch Number
BCCP0159
BCCN3604
BCCL8890
BCCL6333
BCCJ3707

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Kristine Hardy et al.
Free radical biology & medicine, 37(10), 1550-1563 (2004-10-13)
Antioxidants can inhibit the proliferation of T lymphocytes induced by mitogens. This has been postulated to be due to their scavenging of reactive oxygen species which may act as second messengers in the antigen-induced signaling cascade leading to cell proliferation.
Vicente Sancenón et al.
The Journal of biological chemistry, 279(15), 15348-15355 (2004-01-17)
Copper plays a dual role in aerobic organisms, as both an essential and a potentially toxic element. To ensure copper availability while avoiding its toxic effects, organisms have developed complex homeostatic networks to control copper uptake, distribution, and utilization. In
Tomoo Shirabe et al.
Analytical chemistry, 80(23), 9360-9362 (2009-06-25)
A novel method has been devised for the determination of phytochelatins (PCs), heavy-metal-tolerant peptides produced by higher plants and algae. The method is based on the facts that fluorescence of bathocuproine disulfonate (BCS) is quenched by Cu(I) ions as a
Simple procedure for the single sample determination of serum copper and iron.
B ZAK
Clinica chimica acta; international journal of clinical chemistry, 3(4), 328-334 (1958-07-01)
Dazhi Cen et al.
Journal of medicinal chemistry, 47(27), 6914-6920 (2004-12-24)
The alcohol-abuse deterrent disulfiram (DSF) is shown to have a highly selective toxicity against melanoma in culture, inducing a largely apoptotic response, with much lower toxicity against several other cell lines. Melanoma cell lines derived from different stages (radial, vertical
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