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Merck

B7901

Ácido bórico

suitable for electrophoresis, ≥99.5%

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Fórmula lineal:
H3BO3
Número CAS:
Peso molecular:
61.83
PubChem Substance ID:
eCl@ss:
38120104
UNSPSC Code:
12161700
NACRES:
NA.25
EC Number:
233-139-2
MDL number:
Assay:
≥99.5%
Form:
powder
Grade:
electrophoresis grade
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grade

electrophoresis grade

Quality Level

vapor pressure

2.6 mmHg ( 20 °C)

assay

≥99.5%

form

powder

technique(s)

electrophoresis: suitable

impurities

≤0.005% Insoluble in methanol

pH

8.2-10.1

mp

160 °C (dec.) (lit.)

solubility

H2O: 40 mg/mL, clear, colorless

density

1.43 g/cm3 at 20 °C

anion traces

chloride (Cl-): ≤0.001%, phosphate (PO43-): ≤0.001%, sulfate (SO42-): ≤0.01%

cation traces

Ca: ≤0.005%, Fe: ≤0.001%, heavy metals (as Pb): ≤0.001%

suitability

suitable for electrophoresis (as a reagent)

storage temp.

room temp

SMILES string

OB(O)O

InChI

1S/BH3O3/c2-1(3)4/h2-4H

InChI key

KGBXLFKZBHKPEV-UHFFFAOYSA-N

General description

Boric acid is a weak acid and is widely used in multi-purpose solutions (MPS) as a buffering agent. It is less toxic and non-volatile in nature.

Application

Boric acid has been used as a component of tris borate buffer:
  • for native polyacrylamide gel electrophoresis (PAGE) and denaturing urea-PAGE of tRNA samples(80)
  • for urea-polyacrylamide electrophoresis of RNA samples(81)
  • for agarose gel electrophoresis of DNA samples(82)

Biochem/physiol Actions

Boric acid is used in the periodontal therapy as an irrigation solution as it elicits bactericidal effects in microbial biofilms in root canal. Boric acid may favor osteoblastic activity and inhibit bone loss. It inhibits Candida albicans fungal infection and has potential to treat vaginal infection.


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pictograms

Health hazard

signalword

Danger

hcodes

Hazard Classifications

Repr. 1B

Clase de almacenamiento

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges



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Antifungal mechanisms supporting boric acid therapy of Candida vaginitis
De Seta F, et al.
The Journal of Antimicrobial Chemotherapy, 63(2), 325-336 (2008)
Nonclinical safety evaluation of boric acid and a novel borate-buffered contact lens multi-purpose solution, Biotrue? multi-purpose solution
Lehmann DM, et al.
Contact Lens & Anterior Eye : the Journal of the British Contact Lens Association, 33, S24-S32 (2010)
Antibacterial effect of different concentration of boric acid against enterococcus faecalis biofilms in root canal
Zan R, et al.
Marmara Dental Journal, 2, 76-80 (2013)