D0256
Dulcitol
≥99% (GC)
Sinónimos:
Dulcite, Galactitol
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Acerca de este artículo
Fórmula empírica (notación de Hill):
C6H14O6
Número CAS:
Peso molecular:
182.17
UNSPSC Code:
12352201
NACRES:
NA.25
PubChem Substance ID:
EC Number:
210-165-2
Beilstein/REAXYS Number:
1721903
MDL number:
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Permítanos ayudarleInChI key
FBPFZTCFMRRESA-GUCUJZIJSA-N
InChI
1S/C6H14O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3-12H,1-2H2/t3-,4+,5+,6-
SMILES string
OC[C@@H](O)[C@H](O)[C@H](O)[C@@H](O)CO
assay
≥99% (GC)
form
crystals
sweetness
<0.6 × sucrose
color
white
solubility
water: 50 mg/mL, clear, colorless
Quality Level
Application
Dulcitol (Galactitol), a sugar alcohol derived through reduction of galactose, is important in studies related to cataract formation, hepatosplenomegaly and mental retardation. It is used as a substrate to identify, differentiate and characterize galactitol dehydrogenase(s). Galactitol may be used as a reference compound in analytical procedures developed to analyze sugar alcohols in plants and food.
Biochem/physiol Actions
A sugar alcohol and slightly sweet tastant for human taste cells.
Other Notes
To gain a comprehensive understanding of our extensive range of Sugar alcohols for your research, we encourage you to visit our Carbohydrates Category page.
Clase de almacenamiento
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Richard F G Fröhlich et al.
Bioorganic & medicinal chemistry letters, 21(22), 6872-6875 (2011-10-07)
N-(Dansylamino)hexylaminocarbonylpentyl-1,5-dideoxy-1,5-imino-D-galactitol, a strong competitive inhibitor of β-galactosidase, enhances residual β-galactosidase activities in fibroblasts and serves as lead en route to diagnostic compounds for tracking the fate of mutant β-gal as well as aberrant GM1 gangliosides by live cell imaging.
C Jakobs et al.
Pediatric research, 18(8), 714-718 (1984-08-01)
A stable isotope dilution assay for galactitol in amniotic fluid has been developed using selected ion monitoring chemical ionization gas chromatography-mass spectrometry of the hexaacetate derivative. [1,1-2H2]Galactitol was synthesized for use as the internal standard. Galactitol is a component of
Joanne Hughes et al.
The Journal of pediatrics, 154(5), 721-726 (2009-02-03)
To determine the long-term outcome of dietary intervention in siblings from 14 Irish families with classical galactosemia (McKusick 230400), an autosomal recessive disorder of carbohydrate metabolism and galactose-1-phosphate uridyltransferase (GALT) deficiency. Outcomes in siblings on dietary galactose restriction were studied
Ignasi Barba et al.
Investigative ophthalmology & visual science, 51(9), 4416-4421 (2010-04-09)
To explore the metabolic profile of vitreous fluid of patients with proliferative diabetic retinopathy (PDR) using 1H-NMR-based metabonomic analysis. 1H-NMR spectra were acquired from vitreous samples obtained during vitrectomy from 22 patients with type 1 diabetes with PDR and from
Peter F Kador et al.
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 25(4), 299-308 (2009-05-20)
The two most widely investigated animal models for diabetic retinopathy (DR) are the rat and dog. In dogs, aldose reductase (AR) is present only in retinal capillary pericytes and their destruction has been linked to polyol accumulation and resulting apoptosis.
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