D7571
Dimaprit dihydrochloride
≥98% (NMR)
Sinónimos:
Carbamimidothioic acid, 3-(dimethylamino)propyl ester, hydrochloride (1:2), Dimaprit-2HCl
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Acerca de este artículo
Fórmula empírica (notación de Hill):
C6H15N3S · 2HCl
Número CAS:
Peso molecular:
234.19
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
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Permítanos ayudarleInChI
1S/C6H15N3S.2ClH/c1-9(2)4-3-5-10-6(7)8;;/h3-5H2,1-2H3,(H3,7,8);2*1H
SMILES string
Cl.Cl.CN(C)CCCSC(N)=N
InChI key
DFWCPLGXFMSUCW-UHFFFAOYSA-N
assay
≥98% (NMR)
form
powder
color
white to off-white
solubility
H2O: ≥50 mg/mL
originator
Roche
storage temp.
−20°C
Quality Level
Biochem/physiol Actions
Selective histamine receptor H2 agonist.
The histamine H2 receptor influences various cardiovascular responses, including vasodilation and cardiac rhythm, regulates gastric acid secretion, and also plays a role in the immune system by inhibiting antibody production, T cell proliferation and cytokine production. Histamine receptors are members of the GPCR family, and H2 mediates cell signaling via internalization and interaction with the GTPase dynamin.
Features and Benefits
This compound is featured on the Histamine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
This compound was developed by Roche. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Clase de almacenamiento
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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