E1631

β-Estradiol 17-valerate

Name: β-Estradiol 17-valerate
Brand: SIGMA

≥98% (HPLC), powder

Sinónimos:

1,3,5(10)-Estratriene-3,17β-diol 17-pentanote

Iniciar sesión para ver los precios por organización y contrato.

Seleccione un Tamaño

Todas las fotos(1)

About This Item

Fórmula empírica (notación de Hill):

C₂₃H₃₂O₃

Número CAS:

979-32-8

Peso molecular:

356.50

NACRES:

NA.77

PubChem Substance ID:

24894423

UNSPSC Code:

41116107

EC Number:

213-559-2

MDL number:

MFCD00056541

Beilstein/REAXYS Number:

2480357

Nombre del producto

β-Estradiol 17-valerate, ≥98%

InChI key

RSEPBGGWRJCQGY-UHFFFAOYSA-N

InChI

1S/C23H32O3/c1-3-4-5-22(25)26-21-11-10-20-19-8-6-15-14-16(24)7-9-17(15)18(19)12-13-23(20,21)2/h7,9,14,18-21,24H,3-6,8,10-13H2,1-2H3

SMILES string

CCCCC(=O)OC1CCC2C3CCc4cc(O)ccc4C3CCC12C

biological source

synthetic

assay

≥98%

form

powder

technique(s)

ELISA: suitable

solubility

acetone: 25 mg/mL, hazy, colorless

shipped in

ambient

storage temp.

room temp

Quality Level

100

¿Está buscando productos similares? Visita Guía de comparación de productos

Categorías relacionadas

Pequeñas moléculas bioactivas

Application

β-Estradiol 17-valerate has been used:

in an in-vivo assay, to synchronize the estrus cycle in athymic nude mice, to study the effect of recombinant pigment epithelium-derived factor (rPEDF) on induced ectopic fibroid lesions
to study the influence of ovarian hormones on type II cGMP-dependent protein kinase (Prkg2) expression in mice
to induce growth of estrogen-dependent tumor cells in athymic nude mice to establish a breast cancer mouse model

Biochem/physiol Actions

Estradiol valerate is observed to be useful for treating menopausal climacteric symptoms. β-Estradiol 17-valerate is used as a source of 17β-estradiol (E2) in in vitro fertilization, hormone replacement therapy, contraceptive drugs, to study reproductive disorders in animal models. It serves as growth promoter in animal farming. β-Estradiol 17-valerate is also used to culture single-sex population among fish. Studies in rats show that β-Estradiol 17-valerate has negative effects on the estrus cycle pattern.

General description

β-Estradiol 17-valerate is a synthetic estrogen.

pictograms

GHS08,GHS09

signalword

Warning

hcodes

H351,H361fd,H362,H410

pcodes

P201 - P202 - P260 - P263 - P273 - P308 + P313

Hazard Classifications

Aquatic Chronic 1 - Carc. 2 - Lact. - Repr. 2

Clase de almacenamiento

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

ppe

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges

Elija entre una de las versiones más recientes:

Certificados de análisis (COA)

Lot/Batch Number

¿No ve la versión correcta?

Si necesita una versión concreta, puede buscar un certificado específico por el número de lote.

Busque por un COA

¿Ya tiene este producto?

Encuentre la documentación para los productos que ha comprado recientemente en la Biblioteca de documentos.

Visite la Librería de documentos

Effect of estrogen and testosterone replacement therapy on cognitive fatigue.

Marika Christina Möller et al.

Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 29(2), 173-176 (2012-10-26)

Both estrogen and testosterone insufficiency has been associated with reduced psychological well-being including fatigue. However, hormonal replacement studies on fatigue are rare. Therefore, we wanted to study the effect of testosterone and estrogen replacement therapy on cognitive fatigue and the

Temporal window in which exposure to estradiol permanently modifies ovarian function causing polycystic ovary morphology in rats.

Gonzalo Cruz et al.

Fertility and sterility, 98(5), 1283-1290 (2012-08-03)

To investigate the developmental window in which E(2) exposure produces irreversible changes in ovarian function resulting in polycystic ovary. Basic experimental study. University animal laboratory. Thirty Sprague-Dawley rats were administered a single E(2) valerate dose (10 mg/kg of weight) at

Estradiol valerate and dienogest: a novel four-phasic oral contraceptive pill effective for pregnancy prevention and treatment of heavy menstrual bleeding.

Elizabeth Micks et al.

Women's health (London, England), 7(5), 513-524 (2011-09-02)

Estradiol valerate and dienogest have been combined to create a novel four-phasic oral contraceptive pill effective for both pregnancy prevention and treatment of heavy menstrual bleeding. This formulation represents the only oral contraceptive pill available in the USA containing an

Predictive markers for mammoplasty and a comparison of side effect profiles in transwomen taking various hormonal regimens.

L J Seal et al.

The Journal of clinical endocrinology and metabolism, 97(12), 4422-4428 (2012-10-12)

Breast development in transwomen is an important issue, affecting general psychological functioning. Current hormonal therapies are imperfect, with 60% of patients requesting mammoplasty. Interventions included the following: 1) comparing the effects on transwomen's requests for mammoplasty of estrogen valerate, ethinylestradiol

β-estradiol 17-valerate affects embryonic development and sexual differentiation in Japanese medaka (Oryzias latipes).

Bingli Lei et al.

Aquatic toxicology (Amsterdam, Netherlands), 134-135, 128-134 (2013-04-24)

β-estradiol 17-valerate (EV) is a synthetic estrogen widely used in combination with other steroid hormones in hormone replacement therapy drugs and is detected in natural waters. Although EV is known as an estrogenic chemical, there is still a lack of

Ver todos los artículos relacionados

Nuestro equipo de científicos tiene experiencia en todas las áreas de investigación: Ciencias de la vida, Ciencia de los materiales, Síntesis química, Cromatografía, Analítica y muchas otras.

Póngase en contacto con el Servicio técnico