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EMU093101

MISSION® esiRNA

targeting mouse Arhgap4

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NACRES:
NA.51
UNSPSC Code:
41105324
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description

Powered by Eupheria Biotech

Quality Level

100

product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

GCAGCATCAGCAAAAACAAAGTCTTCTCCCGGGGACCTGGGGCTCCAATTTCCCCCTCAACCTCCCATCCCCAGGGTCCAGATTCAACTCGCAAGCCAGTCTGAGGCAGCTTACCTCCAGCAGCCACCACCAAGCCCACCATTCCACATAGGCCTATTGCTTCACCTCAGCCCTCTTCTAGGTCTCTTGGGAGGTAGCAAAGGAAGGAAGCTGGAGATGAGCTCCTCTTATGCCTTTGCTTGGAAGCCTTGGGCTGTGGCTGTGAAATATGGAAGTGGCAGTAATTCATAAAGACCCCATGTGCTGGTTGCTGTTGTAATAGCCTGTGCTGTTTGGGGGGCGCTGAACAGGTAGGGTGCAGGGCAACTCCCAGAGCCTGCACTGCTAGAGACCAGATGCCAA

Ensembl | mouse accession no.

ENSMUSG00000031389

NCBI accession no.

NM_138630

shipped in

ambient

storage temp.

−20°C

Gene Information

mouse ... ARHGAP4(12000), Arhgap4(171207)

General description

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

Clase de almacenamiento

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

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Na Li et al.
Nature cell biology, 16(11), 1080-1091 (2014-10-27)
Cyclin C was cloned as a growth-promoting G1 cyclin, and was also shown to regulate gene transcription. Here we report that in vivo cyclin C acts as a haploinsufficient tumour suppressor, by controlling Notch1 oncogene levels. Cyclin C activates an
Jennifer Munkley et al.
Oncotarget, 6(33), 34358-34374 (2015-10-10)
Patterns of glycosylation are important in cancer, but the molecular mechanisms that drive changes are often poorly understood. The androgen receptor drives prostate cancer (PCa) development and progression to lethal metastatic castration-resistant disease. Here we used RNA-Seq coupled with bioinformatic