I1771
Interleukin-13 human
≥97% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture
Sinónimos:
IL-13
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Servicio técnico
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Permítanos ayudarlebiological source
human
Quality Level
recombinant
expressed in E. coli
assay
≥97% (SDS-PAGE)
form
lyophilized powder
potency
<10.000 ng/mL ED50
mol wt
12 kDa
packaging
pkg of 10 μg
technique(s)
cell culture | mammalian: suitable
impurities
endotoxin, tested
color
white
UniProt accession no.
storage temp.
−20°C
Gene Information
human ... IL13(3596)
Biochem/physiol Actions
IL-13 is known to be overexpressed in glioblastoma tumors and cell lines. Elevated IL-13 expression is also observed in parasitic infections. It stimulates fibrosis in many infectious diseases, and acts as a profibrogenic factor.
Interleukin-13 is a pleiotropic cytokine produced by activated Th2 cells in the mouse and human. IL-13 is secreted mainly as an unglycosylated protein of 132 amino acids with a molecular weight of 10,000 daltons. A 4.3kb DNA fragment of the mouse IL-13 gene was sequenced and occurs as a single copy mapping a chromosome 11. In the human, a 4.6 kb DNA segment of the IL-13 gene occurs as a single copy and maps to chromosome 5. IL-13 induces B cell proliferation and also induces IgE switching. The proliferative activity of human and mouse IL-13 products are tested in culture using the human erythroleukemic cell line TF-1.
Physical form
Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing 250 μg BSA.
Clase de almacenamiento
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Instructions
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