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Merck

M8770

Anti-Mouse IgG1 (heavy chain specific) antibody produced in goat

affinity isolated antibody, lyophilized powder

Sinónimos:

Anti-Mouse Igg1, Heavy Chain Specific Secondary Antibody, Heavy Chain Specific Secondary Antibody - Anti-Mouse IgG1 (heavy chain specific) antibody produced in goat

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UNSPSC Code:
12352203
NACRES:
NA.46
MDL number:
MFCD00162649
Conjugate:
unconjugated
Clone:
polyclonal
Application:
Ouchterlony double diffusion
Technique(s):
Ouchterlony double diffusion: suitable
Citations:
13

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Nombre del producto

Anti-Mouse IgG1 (heavy chain specific) antibody produced in goat, affinity isolated antibody, lyophilized powder

biological source

goat

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

secondary antibodies

clone

polyclonal

form

lyophilized powder

technique(s)

Ouchterlony double diffusion: suitable

storage temp.

2-8°C

target post-translational modification

unmodified

Quality Level

200
300

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Application

Anti-Mouse IgG1 (heavy chain specific) antibody is suitable for use in immunoelectrophoresis and Ouchterlony double diffusion. The antibody may also be used in immunoblot .
Anti-Mouse IgG1 (heavy chain specific) antibody produced in goat has been used in immunohistochemistry and enzyme-linked immunosorbent assay (ELISA)

Biochem/physiol Actions

Digestion of IgG by papain results in the generation of fragment antigen-binding (Fab). Pepsin digestion of IgG results in fragment crystallizable (fc). IgG1 is most abundant of IgG types and its deficiency results in hypogammaglobulinemia.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

Immunoglobulin IgG is a glycoprotein antibody with two light chains and a pair of identical heavy chains.

Immunogen

Mouse IgG1 (myeloma protein)

Physical form

Lyophilized from 0.01 M phosphate buffered saline, pH 7.2.

Preparation Note

Reconstitute with 0.135 M sodium chloride.

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Clase de almacenamiento

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificados de análisis (COA)

Lot/Batch Number
0000352268
0000352268
SLCM5116
SLCD1897
SLBZ4396

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A H Schrijvers et al.
Cancer research, 53(18), 4383-4390 (1993-09-15)
Using viable cells of a human head and neck squamous cell carcinoma (HNSCC) cell line as immunogen, we developed monoclonal antibody (MAb) U36. Immunohistochemical examination revealed distinct surface labeling of MAb U36 with normal human squamous epithelium and squamous cell
The combined effect of mesenchymal stem cells and resveratrol on type 1 diabetic neuropathy
Wang C, et al.
Experimental and Therapeutic Medicine, 17(5), 3555-3563 (2019)
J Pass et al.
Scandinavian journal of immunology, 58(3), 298-305 (2003-09-03)
The urokinase receptor (uPAR) is a glycolipid-anchored cell surface glycoprotein that plays a central role in extracellular proteolysis during tissue remodeling processes including cancer invasion. Furthermore, uPAR is found on the surface of both dendritic cells (DCs) and T cells
Louis-P Vézina et al.
Plant biotechnology journal, 7(5), 442-455 (2009-05-09)
Plant-based transient expression is potentially the most rapid and cost-efficient system for the production of recombinant pharmaceutical proteins, but safety concerns associated with plant-specific N-glycosylation have hampered its adoption as a commercial production system. In this article, we describe an
Fei Wang et al.
Oncology letters, 18(2), 1888-1894 (2019-08-20)
Src homologous and collagen (SHC) SH2-binding protein 1 (SHCBP1) is a member of the SHC family, and is overexpressed in numerous types of cancer. In addition, apoptosis serves an important role in the development of cancer. The purpose of this
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