N3013
Nile Red
Powder
Sinónimos:
9-(diethylamino)-5H-benzo[a]phenoxazin-5-one, 9-(diethylamino)benzo[a]phenoxazin-5-one, Nile Blue A Oxazone
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Fórmula empírica (notación de Hill):
C20H18N2O2
Número CAS:
Peso molecular:
318.37
NACRES:
NA.47
PubChem Substance ID:
UNSPSC Code:
12171500
EC Number:
230-966-0
MDL number:
Beilstein/REAXYS Number:
279110
Servicio técnico
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Permítanos ayudarleNombre del producto
Nile Red, Technical grade
grade
technical grade
Quality Level
form
powder
composition
Carbon: 70.0-77.3%
Nitrogen: 7.5-8.8%
technique(s)
titration: suitable
mp
203-205 °C (lit.)
solubility
methanol: 1 mg/mL
λmax
553 nm
application(s)
diagnostic assay manufacturing
hematology
histology
storage temp.
room temp
SMILES string
CCN(CC)c1ccc2N=C3C(Oc2c1)=CC(=O)c4ccccc34
InChI
1S/C20H18N2O2/c1-3-22(4-2)13-9-10-16-18(11-13)24-19-12-17(23)14-7-5-6-8-15(14)20(19)21-16/h5-12H,3-4H2,1-2H3
InChI key
VOFUROIFQGPCGE-UHFFFAOYSA-N
General description
Nile Red is a lipophilic fluorescent benzophenoxazone dye that is metachromatic and solvatochromic. It is an uncharged hydrophobic molecule with the ability to stain and visualize lipid droplets in cells and tissues. It functions as a fluorescent probe for intracellular lipids and hydrophobic domains of proteins. This dye is fluorescent in all organic solvents. Its fluorescence colors range from golden yellow to deep red.
Application
Nile red is widely employed in studies related to lipid metabolism, lipid droplet dynamics, lipid accumulation in cells or tissues, and lipid-based drug delivery systems. Its other applications include:
- identification of microplastics in routine analysis of biological samples.
- detection of lysosomes and lysosome-related organelles, like gut granules in C. elegans intestinal cells.
- it exhibits strong fluorescence enhancement and is used for staining SDS (sodium dodecyl sulphate) gels.
Biochem/physiol Actions
Nile Red is lipophilic in nature and exploits the hydrophobic properties of molecules such as lipids and plastics that fluoresce when excited with certain wavelengths, facilitating quantification and identification.
Clase de almacenamiento
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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