N8130

4-Nitrophenyl acetate

Name: 4-Nitrophenyl acetate
Brand: SIGMA

esterase substrate, chromogenic, ≥98% (TLC), powder or crystals

Sinónimos:

Acetic acid 4-nitrophenyl ester

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About This Item

Fórmula lineal:

CH₃CO₂C₆H₄NO₂

Número CAS:

830-03-5

Peso molecular:

181.15

NACRES:

NA.32

PubChem Substance ID:

24897853

UNSPSC Code:

12352204

EC Number:

212-593-5

MDL number:

MFCD00007326

Beilstein/REAXYS Number:

515874

Nombre del producto

4-Nitrophenyl acetate, esterase substrate

InChI key

QAUUDNIGJSLPSX-UHFFFAOYSA-N

InChI

1S/C8H7NO4/c1-6(10)13-8-4-2-7(3-5-8)9(11)12/h2-5H,1H3

SMILES string

CC(=O)Oc1ccc(cc1)[N+]([O-])=O

assay

≥98% (TLC)

form

powder or crystals

mp

75-77 °C (lit.)

storage temp.

−20°C

Quality Level

200

Gene Information

human ... PON1(5444)

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Application

4-Nitrophenyl acetate has been used:

to evaluate esterase activity in human embryonic kidney cell line
in carbonic anhydrase inhibition assay
to study its conversion to p-nitrophenol (p-NP) by the esterase activity of bovine serum albumin
as a substrate to determine carboxylesterase (CES) activity in mouse liver cells
to study the advantages of bioconjugation of cross-linked enzyme aggregates (CLEAs) and magnetic iron oxide nanoparticles (MIONPs) in magnetic CLEAs matrix

General description

Chromogenic esterase substrate.

pictograms

GHS03,GHS05,GHS07

signalword

Danger

hcodes

H272,H317,H318

pcodes

P210 - P220 - P261 - P280 - P302 + P352 - P305 + P351 + P338

Hazard Classifications

Eye Dam. 1 - Ox. Sol. 3 - Skin Sens. 1

Clase de almacenamiento

5.1B - Oxidizing hazardous materials

wgk

WGK 3

flash_point_f

No data available

flash_point_c

No data available

ppe

Eyeshields, Gloves, type N95 (US)

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Novel Redox-Dependent Esterase Activity (EC 3.1.1.2) for DJ-1: Implications for Parkinson's Disease.

Emmanuel Vázquez-Mayorga et al.

International journal of molecular sciences, 17(8) (2016-08-25)

Mutations the in human DJ-1 (hDJ-1) gene are associated with early-onset autosomal recessive forms of Parkinson's disease (PD). hDJ-1/parkinsonism associated deglycase (PARK7) is a cytoprotective multi-functional protein that contains a conserved cysteine-protease domain. Given that cysteine-proteases can act on both

Isoflurane's Effect on Protein Conformation as a Proposed Mechanism for Preconditioning.

Michelle R Baker et al.

Biochemistry research international, 2011, 739712-739712 (2011-09-16)

Persistent alteration of protein conformation due to interaction with isoflurane may be a novel molecular aspect of preconditioning. We preincubated human serum albumin with isoflurane, dialyzed to release agent, and assessed protein conformation. Susceptibility to chemical modification by methylglyoxal and

Immunomodulatory, antiglycation and anti-ulcerative properties of Ruellia squarrosa Fenzl Acanthaceae

Afzal K, et al.

Tropical Journal of Pharmaceutical Research, 16(8), 1751-1755 (2017)

Impact of diet on irinotecan toxicity in mice

Mallick P, et al.

Chemico-Biological Interactions, 291, 87-94 (2018)

An efficient method for transient gene expression in monocots applied to modify the Brachypodium distachyon cell wall.

Oksana Fursova et al.

Annals of botany, 110(1), 47-56 (2012-05-17)

Agrobacterium-mediated transformation is widely used to produce insertions into plant genomes. There are a number of well-developed Agrobacterium-mediated transformation methods for dicotyledonous plants, but there are few for monocotyledonous plants. Three hydrolase genes were transiently expressed in Brachypodium distachyon plants

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Product Information Sheet - N8130

Product Information Sheet

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