N8133
Nerve Growth Factor from Vipera lebetina venom
lyophilized powder, suitable for cell culture
Sinónimos:
NGF
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Biological source:
Vipera Lebetina
Form:
lyophilized powder
Mol wt:
protein 32.5 kDa
Impurities:
<10 EU/vial
Servicio técnico
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Permítanos ayudarleNombre del producto
Nerve Growth Factor from Vipera lebetina venom, NGF, lyophilized powder, suitable for cell culture
biological source
Vipera Lebetina
Quality Level
form
lyophilized powder
potency
0.2-20 μg/mL ED50/EC50
quality
endotoxin tested
mol wt
protein 32.5 kDa
packaging
pkg of 0.1 mg
technique(s)
cell culture | mammalian: suitable
impurities
<10 EU/vial
color
white to off-white
UniProt accession no.
storage temp.
−20°C
Physical form
Lyophilized from a 0.2 μm filtered solution in sodium acetate buffer.
Preparation Note
Isolated from the snake venom of V. lebetina.
Analysis Note
The biological activity of Nerve Growth Factor (NGF) from Vipera lebetina venom is measured in a cell proliferation assay using PC-12 cells.
Clase de almacenamiento
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Contenido relacionado
Datasheet
Lucy Hepburn et al.
Science (New York, N.Y.), 346(6209), 641-646 (2014-11-02)
Many key components of innate immunity to infection are shared between Drosophila and humans. However, the fly Toll ligand Spaetzle is not thought to have a vertebrate equivalent. We have found that the structurally related cystine-knot protein, nerve growth factor
Giusi Prencipe et al.
Journal of immunology (Baltimore, Md. : 1950), 192(7), 3345-3354 (2014-03-04)
Nerve growth factor (NGF) levels are highly increased in inflamed tissues, but their role is unclear. We show that NGF is part of a regulatory loop in monocytes: inflammatory stimuli, while activating a proinflammatory response through TLRs, upregulate the expression
Yu-Jung Chang et al.
Biochimica et biophysica acta, 1830(8), 4130-4136 (2013-04-16)
Neurotrophins are important regulators for neural development and regeneration. Nerve growth factor (NGF) therapy has been tested in various models of neural injury and degeneration. However, whether NGF can reach target tissues and maintain effective concentration for a certain period