N9876
4-Nitrophenyl butyrate
lipase substrate, chromogenic, esterase substrate, ≥98%, liquid
Sinónimos:
p-Nitrophenyl butyrate, Butyric acid 4-nitrophenyl ester
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Fórmula empírica (notación de Hill):
C10H11NO4
Número CAS:
Peso molecular:
209.20
NACRES:
NA.83
PubChem Substance ID:
UNSPSC Code:
12352204
MDL number:
Beilstein/REAXYS Number:
1879729
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Permítanos ayudarleNombre del producto
4-Nitrophenyl butyrate, ≥98%
InChI
1S/C10H11NO4/c1-2-3-10(12)15-9-6-4-8(5-7-9)11(13)14/h4-7H,2-3H2,1H3
SMILES string
CCCC(=O)Oc1ccc(cc1)[N+]([O-])=O
InChI key
DVDUMIQZEUTAGK-UHFFFAOYSA-N
assay
≥98%
form
liquid
density
1.19 g/mL at 20 °C (lit.)
storage temp.
−20°C
Quality Level
General description
4-Nitrophenyl butyrate is a substrate for esterase, and lipase enzyme. Hydrolysis of 4-nitrophenyl butyrate by these enzymes releases the chromophore, 4-nitrophenolate which is spectrophotometrically analysed at 415 nm.
Application
4-nitrophenyl butyrate has been used:
- as a substrate for esterase activity in monocyte-derived macrophage cell line in response to polyethylene
- as a substrate for mycobacterial phospholipase A and mycobacterial cutinase activity
- as a substrate to determine the effect of buffers and solvents on human carboxylesterase
signalword
Warning
hcodes
Hazard Classifications
Skin Sens. 1
Clase de almacenamiento
10 - Combustible liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
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Differential response to chemically altered polyethylene by activated mature human monocyte-derived macrophages
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Biomaterials, 23(17), 3595-3602 (2002)
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The lipase from Pseudomonas fluorescens (PFL) has been immobilized on glyoxyl-octyl agarose and compared to the enzyme immobilized on octyl-agarose. Thus, PFL was immobilized at pH 7 on glyoxyl-octyl support via lipase interfacial activation and later incubated at pH 10.5 for 20 h
Geum Jin Kim et al.
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Since 2016, the invasive halophyte Spartina anglica has been colonizing mudflats along the western coast of South Korea. In order to minimize costs on S. anglica expansion management and waste-treatment of collected biomass, the potential application of the collected biomass
Li-Chun Wang et al.
Journal of food and drug analysis, 26(3), 973-984 (2018-07-07)
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β-sitostanol esters, used as dietary complement for decreasing cholesterol absorption, have been synthesized at 28°C via direct esterification or transesterification catalyzed by the versatile lipase/sterol esterase from the ascomycete fungus O. piceae. Direct esterification was conducted in biphasic isooctane: water
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