O1257
Oleic Acid-Water Soluble
powder, BioReagent, suitable for cell culture
Sinónimos:
Oleic Acid–Cyclodextrin Complex
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Permítanos ayudarlebiological source
synthetic (organic)
Quality Level
product line
BioReagent
form
powder
composition
Oleic acid, ~30 mg/g (balance methyl-β-cyclodextrin)
technique(s)
cell culture | mammalian: suitable
solubility
H2O: 50 mg/mL, clear to slightly hazy
storage temp.
−20°C
SMILES string
CCCCCCCC\C=C/CCCCCCCC(O)=O
InChI
1S/C18H34O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h9-10H,2-8,11-17H2,1H3,(H,19,20)/b10-9-
InChI key
ZQPPMHVWECSIRJ-KTKRTIGZSA-N
Gene Information
human ... SOAT1(6646), SOAT2(8435)
Application
Oleic Acid-Water Soluble has been used:
- to prepare the FFAs (free fatty acids) mixture for cell treatment
- to investigate its effect on the solute carrier family 2 member 4 (SLC2A4)/GLUT4 expression in L6 muscle cells and as potential transcriptional regulators
- in the preparation of fatting media for the induction of in vitro steatosis in primary human hepatocytes
Other Notes
Methyl-β-cylodextran binding improves the solubility and delivery of Oleic acid in culture media.
Clase de almacenamiento
10 - Combustible liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type ABEK (EN14387) respirator filter
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Oleic and linoleic fatty acids downregulate Slc2a4/GLUT4 expression via NFKB and SREBP1 in skeletal muscle cells
Poletto A C, et al.
Molecular and Cellular Endocrinology, 401(12), 65-72 (2015)
A20 attenuates FFAs-induced lipid accumulation in nonalcoholic steatohepatitis
Ai L, et al.
International Journal of Biological Sciences, 11(12), 1436-1436 (2015)
Shuo Li et al.
International journal of biological sciences, 17(15), 4165-4175 (2021-11-23)
Background: Inflammation and apoptosis play a crucial role in the progression of nonalcoholic steatohepatitis (NASH). Suppressor of cytokine signaling 2 (SOCS2) is one of classic negative regulators of cytokine signaling, which has recently been described as anti-inflammatory mediators. However, the