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SR-95531

≥98% (HPLC), GABAA receptor antagonist , powder

Sinónimos:

2-(3-Carboxypropyl)-3-amino-6-(4 methoxyphenyl)pyridazinium bromide, Gabazine

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Fórmula empírica (notación de Hill):
C15H18BrN3O3
Número CAS:
104104-50-9
Peso molecular:
368.23
UNSPSC Code:
12352200
PubChem Substance ID:
24278819
NACRES:
NA.77
MDL number:
MFCD00055135
Assay:
≥98% (HPLC)
Form:
powder
Quality level:
100
Servicio técnico
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Nombre del producto

SR-95531, ≥98% (HPLC), powder

Quality Level

100

assay

≥98% (HPLC)

form

powder

color

white

solubility

H2O: >10 mg/mL

SMILES string

[Br-].COc1ccc(cc1)-c2ccc(N)[n+](CCCC(O)=O)n2

InChI

1S/C15H17N3O3.BrH/c1-21-12-6-4-11(5-7-12)13-8-9-14(16)18(17-13)10-2-3-15(19)20;/h4-9,16H,2-3,10H2,1H3,(H,19,20);1H

InChI key

GFZHNFOGCMEYTA-UHFFFAOYSA-N

Gene Information

human ... GABRA1(2554), GABRA2(2555), GABRA3(2556), GABRA4(2557), GABRA5(2558), GABRA6(2559), GABRB1(2560), GABRB2(2561), GABRB3(2562)
rat ... Gabra2(29706)

Biochem/physiol Actions

SR-95531 is a specific GABAA receptor antagonist that does not affect GABA-transaminase or glutamate-decarboxylase activities.

Features and Benefits

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
This compound is featured on the GABAA Receptors and GABAC Receptors pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Clase de almacenamiento

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificados de análisis (COA)

Lot/Batch Number
0000222074
0000222074
0000158055
0000158056

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Relatively few studies have examined plasticity of inhibitory neuronal networks following stroke in vivo, primarily due to the inability to selectively monitor inhibition. We assessed the structure of parvalbumin (PV) interneurons during a 5 min period of global ischemia and
Ian Duguid et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 32(32), 11132-11143 (2012-08-10)
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