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407314 Anti-Integrin β₃ (Ab-1) Mouse mAb (290.5C10)

Anti-Integrin β₃ (Ab-1) Mouse mAb (290.5C10) MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Anti-CD61

407314
  
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      Overview

      Replacement Information

      Key Spec Table

      Species ReactivityHostAntibody Type
      HMMonoclonal Antibody
      Description
      Overview

      This product has been discontinued.



      Recognizes the β3 integrin subunit in αvβ3 and αllbβ3 integrin protein complexes.
      Catalogue Number407314
      Brand Family Calbiochem®
      SynonymsAnti-CD61
      References
      ReferencesHynes, R.O. 1992. Cell. 69, 11.
      Phillips, D.R., et al. 1991. Cell. 65, 359.
      Albelda, S.M. and Buck, C.A. 1990. FASEB J. 4, 2868.
      Buck, C.A. and Horwitz, A.F. 1987. Ann. Rev. Cell Biol. 3, 179.
      Hynes, R.O. 1987. Cell. 45, 549.
      Product Information
      FormLiquid
      FormulationUndiluted ascites.
      PreservativeNone
      Quality LevelMQ100
      Applications
      Key Applications Enzyme-Linked Immunosorbent Assay
      Flow Cytometry
      Immunoblotting (Western Blotting)
      Immunoprecipitation
      Paraffin Sections
      Application NotesELISA (see comments)
      Flow Cytometry (1:50-1:100)
      Immunoblotting (1:50-1:100)
      Paraffin Sections (1:50-1:100)
      Immunoprecipitation (1:50-1:100)
      Application CommentsThis antibody has also been reported to work for ELISA. Variables associated with assay conditions will dictate the proper working dilution.
      Biological Information
      Immunogenβ₃ integrin from M21 melanoma cells
      ImmunogenHuman
      Clone290.5C10
      HostMouse
      IsotypeIgG₁
      Species Reactivity
      • Human
      Antibody TypeMonoclonal Antibody
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Dry Ice Only
      Toxicity Standard Handling
      Storage -20°C
      Avoid freeze/thaw Avoid freeze/thaw
      Do not freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      407314 0

      Documentation

      Anti-Integrin β₃ (Ab-1) Mouse mAb (290.5C10) SDS

      Title

      Safety Data Sheet (SDS) 

      Anti-Integrin β₃ (Ab-1) Mouse mAb (290.5C10) Certificates of Analysis

      TitleLot Number
      407314

      References

      Reference overview
      Hynes, R.O. 1992. Cell. 69, 11.
      Phillips, D.R., et al. 1991. Cell. 65, 359.
      Albelda, S.M. and Buck, C.A. 1990. FASEB J. 4, 2868.
      Buck, C.A. and Horwitz, A.F. 1987. Ann. Rev. Cell Biol. 3, 179.
      Hynes, R.O. 1987. Cell. 45, 549.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision06-August-2007 RFH
      SynonymsAnti-CD61
      ApplicationELISA (see comments)
      Flow Cytometry (1:50-1:100)
      Immunoblotting (1:50-1:100)
      Paraffin Sections (1:50-1:100)
      Immunoprecipitation (1:50-1:100)
      DescriptionMouse monoclonal antibody supplied as undiluted ascites. Recognizes the β3 integrin subunit in αvβ3 and αllbβ3 integrin protein complexes.
      BackgroundThe integrins are a family of more than 23 heterodimeric transmembrane proteins that mediate cell-cell adhesions as well as cell-substratum adhesions and signal transduction processes. Integrins are heterodimers consisting of noncovalently associated α and β subunits. CD61 non-covalently associates with CD41 (αIlb integrin) and is expressed by megakaryocytes and platelets. The CD61/CD41 complex acts as a receptor for such adhesive ligands as fibronectin, fibrinogen and von Willebrand factor during platelet stimulation.
      HostMouse
      Immunogen speciesHuman
      Immunogenβ₃ integrin from M21 melanoma cells
      Clone290.5C10
      IsotypeIgG₁
      Specieshuman
      FormLiquid
      FormulationUndiluted ascites.
      PreservativeNone
      CommentsThis antibody has also been reported to work for ELISA. Variables associated with assay conditions will dictate the proper working dilution.
      Storage Avoid freeze/thaw
      -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
      Toxicity Standard Handling
      ReferencesHynes, R.O. 1992. Cell. 69, 11.
      Phillips, D.R., et al. 1991. Cell. 65, 359.
      Albelda, S.M. and Buck, C.A. 1990. FASEB J. 4, 2868.
      Buck, C.A. and Horwitz, A.F. 1987. Ann. Rev. Cell Biol. 3, 179.
      Hynes, R.O. 1987. Cell. 45, 549.