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852090 Fmoc-Tyr(PO(NMe₂)₂)-OH

Fmoc-Tyr(PO(NMe₂)₂)-OH Novabiochem®. CAS 172611-23-3, molar mass 537.55 g/mol.

Fmoc-Tyr(PO(NMe₂)₂)-OH MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
CAS #: 172611-23-3 Molar Mass: 537.55 g/mol Hill Formula: C₂₈H₃₂N₃O₆P
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Overview

Replacement Information

Key Spec Table

CAS #Hill FormulaMolar Mass
172611-23-3C₂₈H₃₂N₃O₆P537.55 g/mol
Description
Catalogue Number852090
Replaces04-12-1205
Brand Family Novabiochem®
Alternate Names
  • N-α-Fmoc-O-(bis-dimethylamino-phosphono)-L-tyrosine
Background InformationFmoc-Tyr(PO(NMe2)2)-OH is a useful derivative for the synthesis of phosphotyrosine-containing peptides by Fmoc SPPS [1]. As the side-chain phosphate group is fully protected, this derivative is compatible with all coupling methods.

Regeneration of phosphotyrosine from the phosphodiamidate is effected by acid catalyzed hydrolysis using 90% aq. TFA.

The product number for this product was previously 04-12-1205.

To obtain a certificate of analysis (CoA) of a lot that begins with the letter "A", please select the option in the right hand menu "Request a COA for Lot#s starting with A".
References
Product Information
CAS number172611-23-3
Hill FormulaC₂₈H₃₂N₃O₆P
Molar Mass537.55 g/mol
Structure formula ImageStructure formula Image
Quality LevelMQ200
Applications
ApplicationFmoc-Tyr(PO(NMe₂)₂)-OH Novabiochem®. CAS 172611-23-3, molar mass 537.55 g/mol.
Biological Information
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Storage class10 - 13 Other liquids and solids
WGKWGK 2 obviously hazardous to water
Safety Information
Product Usage Statements
Storage and Shipping Information
StorageStore at -15°C to -25°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Color (visual)white to slight yellow to beige
Appearance of substance (visual)powder
Identity (IR)passes test
Enantiomeric purity≥ 99.5 % (a/a)
Purity (TLC(0811))≥ 96 %
Assay (HPLC, area%)≥ 96.0 % (a/a)
Solubility (1 mmole in 2 ml DMF)clearly soluble
Assay (acidimetric)≥ 93.0 %
Water (K. F.)≤ 4.5 %
Ethyl acetate (HS-GC)≤ 0.5 %
Acetate (IC)≤ 0.1 %
For TLC-Systems see our General Catalog

Documentation

Fmoc-Tyr(PO(NMe₂)₂)-OH SDS

Title

Safety Data Sheet (SDS) 

Citations

Title
[1] H. G. Chao, et al. (1995) J. Org. Chem., 60, 7710.